α-卡茄碱
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- CAS号:
- 20562-03-2
- 英文名:
- α-Chaconine
- 英文别名:
- CHACONINE;A-CHACONINE;α-Chaconine;CHACONINE, A-;ALPA-CHACONINE;alpha-Chaconin;ALPHA-CHACOCINE;ALPHA-CHACONINE;CHACONINE, ALPHA-;A-CHACONINE WITH TLC
- 中文名:
- α-卡茄碱
- 中文别名:
- 卡茄碱;Α-卡茄碱;Α-查康碱;α-卡茄碱;阿尔法卡茄碱;Α-卡茄碱 标准品;ALPHA-CHACONIN
- CBNumber:
- CB5773055
- 分子式:
- C45H73NO14
- 分子量:
- 852.06
- MOL File:
- 20562-03-2.mol
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α-卡茄碱化学性质
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熔点:
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228-236 °C
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密度:
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1.37±0.1 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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pyridine: 10 mg/mL, clear, very faintly yellow
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酸度系数(pKa):
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12?+-.0.70(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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稳定性:
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Hygroscopic
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LogP:
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8.500 (est)
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α-卡茄碱性质、用途与生产工艺
α-卡茄碱，从Solanum tuberosum L. cv Jayoung 分离的，可在转录水平抑制 COX-2，IL-1β，IL-6 和 TNF-α 表达。α-Chaconine 作用于 RAW 264.7 巨噬细胞，在蛋白和 mRNA 水平上抑制 LPS 诱导的 iNOS 和 COX-2 表达及其启动子活性。α-Chaconine 具有抗炎作用。
α-Chaconine attenuates the transcriptional activity of activator protein-1 (AP-1) by reducing the translocation and phosphorylation of c-Jun.α-Chaconine suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.α-Chaconine also suppresses the phosphorylation of TGF-β-activated kinase-1 (TAK1), which lies upstream of MKK7/JNK signaling.
类别
有毒物质
毒性分级
高毒
急性毒性
腹腔-大鼠 LD50: 84 毫克/公斤; 腹腔-小鼠 LD50: 19 毫克/
可燃性危险特性
热分解辛辣刺激烟雾
储运特性
库房低温通风干燥; 与食品原料分开存放
灭火剂
水,二氧化碳, 泡沫, 干粉
α-卡茄碱
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-129113 | 卡茄碱
α-Chaconine | 20562-03-2 | 1mg | 3500元 |
| 2023/10/26 | HY-129113 | 卡茄碱
α-Chaconine | 20562-03-2 | 5mg | 12500元 |
α-卡茄碱
生产厂家
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α-卡茄碱国内生产厂家
20562-03-2, α-卡茄碱 相关搜索:
- Complex Molecules
- Chiral Building Blocks
- Asymmetric Synthesis
- Alkaloids
- 标准品
- 植物提取物
- C45H73NO14
- Α-卡茄碱 标准品
- Α-卡茄碱
- ALPHA-CHACONIN
- 阿尔法卡茄碱
- Α-查康碱
- α-卡茄碱
- 卡茄碱
- 20562-03-2
- CHACONINE, ALPHA-
- ALPHA-CHACONINE CAS NO.20562-03-2
- β-D-Glucopyranoside, (3β)-solanid-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-
- alpha-Chaconin
- α-Chaconine
- A-CHACONINE
- ALPA-CHACONINE
- ALPHA-CHACONINE
- alpha-chaconine from potato sprouts
- CHACONINE, ALPHA-(SH)
- Solanida-5-ene-3β-yl 2-O,4-O-di(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
- [Solanid-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
- α-Chaconine from potato sprouts
- A-CHACONINE WITH TLC
- ALPHA-CHACOCINE
- ACONINE: -D-GLUCOPYRANOSIDE, (3)-SOLANID-5-EN-3-YL O-6-DEOXY--L-MANNOPYRANOSYL-(1->2)-O-[6-DEOXY--L-MANNOPYRANOSYL-(1->4)]-
- A-CHACONINE FROM POTATO SPROUTS
- CHACONINE, A-
- CHACONINE
- BETA-D-GLUCOPYRANOSIDE, (3)-SOLANID-5-EN-3-YL O-6-DEOXY-L-MANNOPYRANOSYL-(1->2)-O-[6-DEOXY-L-MANNOPYRANOSYL-(1->4)]-