GVYIHPF配体多肽
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- CAS号:
- 25849-90-5
- 英文名:
- 2-8-Angiotensin II, 2-glycine-5-L-isoleucine-
- 英文别名:
- TRV055;2-8-Angiotensin II;2-8-Angiotensin II, 2-glycine-5-L-isoleucine-
- 中文名:
- GVYIHPF配体多肽
- 中文别名:
- GVYIHPF配体多肽
- CBNumber:
- CB58379268
- 分子式:
- C42H57N9O9
- 分子量:
- 831.97
- MOL File:
- 25849-90-5.mol
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GVYIHPF配体多肽化学性质
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沸点:
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1273.8±65.0 °C(Predicted)
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密度:
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1.296±0.06 g/cm3(Predicted)
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酸度系数(pKa):
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3.56±0.10(Predicted)
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GVYIHPF配体多肽性质、用途与生产工艺
TRV055 是 1 型血管紧张素 II 受体 (AT1R) 的 Gq-偏置的配体。TRV055 有效刺激细胞 Gq 介导的信号传导。TRV055 可用于开发 Gq-偏置的 AT1R 激动剂。
TRV055 is a “gain-of-function” ligand that have >10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), “Gq-biased” AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling.
GVYIHPF配体多肽
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-P3136 | TRV055 | | 1 mg | 500元 |
| 2024/04/30 | HY-P3136 | TRV055 | | 5 mg | 1500元 |
25849-90-5, GVYIHPF配体多肽 相关搜索:
- 目录肽
- C42H57N9O9
- GVYIHPF配体多肽
- 25849-90-5
- 2-8-Angiotensin II
- TRV055
- 2-8-Angiotensin II, 2-glycine-5-L-isoleucine-