183293-82-5
|
|
|
- CAS号:
- 183293-82-5
- 英文名:
- 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid
- 英文别名:
- PD-72953;gemcabene;Hexanoic acid, 6,6'-oxybis[2,2-dimethyl-;Gemcabene,Inhibitor,PD72953,inhibit,PD 72953;6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid;6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethyl-hexanoic acid
- 中文名:
- 183293-82-5
- 中文别名:
- 化合物 T11386L;化合物GEMCABENE
- CBNumber:
- CB61258501
- 分子式:
- C16H30O5
- 分子量:
- 302.41
- MOL File:
- 183293-82-5.mol
|
|
|
183293-82-5化学性质
-
熔点:
-
49-51 °C
-
|
-
沸点:
-
453.6±30.0 °C(Predicted)
-
|
-
密度:
-
1.048±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
DMSO: ≥ 125 mg/mL (413.35 mM)
-
|
-
酸度系数(pKa):
-
4.52±0.45(Predicted)
-
|
183293-82-5性质、用途与生产工艺
Gemcabene (PD-72953)，首创的降脂剂，可降低密度脂蛋白胆固醇 (LDL-C)、降甘油三酯以及升高高密度脂蛋白胆固醇 (HDL-C)，并降低促炎性急性相蛋白，C-反应蛋白 (CRP)，显示抗炎活性。
Gemcabene calcium (PD-72953 calcium) significantly downregulates hepatic mRNA markers of inflammation (TNF-α, MCP-1, MIP-1β, CCR5, CCR2, NF-κB), lipogenesis and lipid modulation (ApoC-III, ACC1, ADH-4, Sulf-2), and fibrosis (TIMP-1 and MMP-2).
183293-82-5
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-109567 | 183293-82-5
Gemcabene | 183293-82-5 | 5mg | 750元 |
| 2024/04/30 | HY-109567 | 183293-82-5
Gemcabene | 183293-82-5 | 10mg | 1250元 |
183293-82-5, 183293-82-5 相关搜索:
- C16H30O5
- 化合物GEMCABENE
- 化合物 T11386L
- 183293-82-5
- Gemcabene,Inhibitor,PD72953,inhibit,PD 72953
- Hexanoic acid, 6,6'-oxybis[2,2-dimethyl-
- PD-72953
- 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethyl-hexanoic acid
- gemcabene
- 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid