(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐

(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐性质、用途与生产工艺

简介

(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸盐酸盐衍生物呈白色或灰白色结晶粉末状，其是合成雷米普利的关键中间体。

制备

以苯甲酰胺和丙酮酸乙酯为原料经缩合、加成反应，合成 2- 苯甲酰氨基 -3(2- 氧代环戊基 ) 丙酸乙酯。 在此基础上，再经水解环合、氢化， 可以得到雷米普利关键中间体 2- 氮杂双环[3.3.0] 辛烷 -3- 羧酸苄酯盐酸盐。其合成反应式如下图：

用途 

雷米普利中间体。

用途 

用于合成雷米普利药物

(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 上下游产品信息

上游原料

下游产品

(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/01/16	B5344	(S,S,S)-2-氮杂双环[3.3.0]辛烷-3-羧酸苄酯盐酸盐 Benzyl (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylate Hydrochloride	87269-87-2	1g	160元
2024/01/16	XW028726987202	(S,S,S)-2-氮杂双环[3.3.0]辛烷-3-羧酸苄酯盐酸盐 (2S,3aS,6aS)-Benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride		5g	443元

(1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 生产厂家

 

87269-87-2, (1S,3S,5S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 相关搜索:

• Pharmaceutical Intermediates
• Pharmaceuticals
• Intermediates & Fine Chemicals
• Chiral Reagents
• Aromatics
• 高端化学
• 化工中间体-化工原料
• 精细化学系列
• 原料药
• 医药中间体
• 手性砌块
• 不对称合成
• (1S,3S,5S)-2-氨杂双环[3,3,0]辛烷3-羧酸苄酯盐酸盐
• (1S,3S,5S)-2-氮环[3,3,0]辛烷-3-羧酸盐酸苄酯
• 雷米普利杂质 标准品
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• 87269-87-2
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• Benzyl (cis, endo) octahydrocyclopenta (Ramipril int)
• (1S, 3S, 5S) -2-azabicyclic [3,3,0] octane-3-carboxylic acid benzyl ester hydrochloride
• (1S,3S,5S)-2-Azabicyclo[3,3,0] –octan-carboxylic acid benzylester hydrochloride
• (1s,3s,5s)-2-azabicyclo(3,3,0)octane-3-carboxylic acid benzy...
• Cyclopenta[b]?pyrrole-2-carboxylic acid, octahydro-, phenylmethyl ester, hydrochloride (1:1), (2S,3aS,6aS)
• (2S,3aS,6aS)-Octahydrocyclopenta[b]
• benzyl (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride
• (1s,3s,5s)-2-azabicyclo(3,3,0)octane-3-carborylic acid benzyl ester
• 6-(phenylmethyl)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride
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• Ramipril Intermediate
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• (S,S,S)-2-Azabicyclo[3,3,0]-Octane-Carboxylic Acid Benzyl Ester Hydroxychloride
• (S,S,S)-2-Azabicyclo-[3,3,0]-octane carboxylic acid benzylester hydrochloride, (S,S,S)-2-Azabicyclo[3,3,0]octane-3-carboxylic acid benzyl ester hydrochloride
• (S,S,S)-Octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester hydrochloride
• (S,S,S)-Octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester HCl
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• (S,S,S)-2-AZABICYCLO[3,3,0]-OCTANE-3-CARBOXYLIC ACID BENZYL ESTER HYDROCHLORIDE
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• (3S)-BENZYL ENDO CIS-2-AZABICYCLO (3,3,0)-OCTANE HYDROCHLORIDE
• (3S)–BENZYL CIS ENDO–2–AZABICYCLO [3.3.0] –OCTANE–3–CARBOXYLATE HYDROCHLORIDE
• (S,S,S)-2-AZABICYCLO (3,3,0) OCTANE CAR&
• (1S, 3S, 5S)-2-Azabicyclo[3,3,0]Octane-3-Carborylic Acid Benzyl Ester hydrochlor
• (1S,3S,5S)-2-azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride