伊诺加群
|
|
|
- CAS号:
- 155415-08-0
- 英文名:
- inogatran
- 英文别名:
- H-314-27;inogatran;Inogatran (H-314-27);Glycine, N-[(1R)-2-[(2S)-2-[[[3-[(aminoiminomethyl)amino]propyl]amino]carbonyl]-1-piperidinyl]-1-(cyclohexylmethyl)-2-oxoethyl]-
- 中文名:
- 伊诺加群
- 中文别名:
- 伊诺加群;化合物 T11659;INOGATRAN (H-314-27)
- CBNumber:
- CB61309557
- 分子式:
- C21H38N6O4
- 分子量:
- 438.56
- MOL File:
- 155415-08-0.mol
|
|
|
伊诺加群化学性质
-
密度:
-
1.36±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
酸度系数(pKa):
-
2.16±0.10(Predicted)
-
|
伊诺加群性质、用途与生产工艺
Inogatran (H-314-27) 是一种合成的 thrombin 抑制剂，主要用于预防动脉和静脉血栓性疾病。
Inogatran (H-314-27; 0.075, 0.25, 0.75 mg/kg, i.v.) results in dose-dependent increases in activated partial thromboplastin time (aPTT), thrombin time (TT), and prothrombin time (PT) in a canine electrolytic injury model of venous thrombosis.
Inogatran dose-dependently inhibits thrombus formation, which is measured as an increase in time to occlusion (TTO) and a decrease in thrombus weight. Inogatran also improves vena caval blood flow and reduces the overall incidence of thrombotic occlusion in a rat model.
伊诺加群
上下游产品信息
上游原料
下游产品
155415-08-0, 伊诺加群 相关搜索:
- 抑制剂
- INOGATRAN (H-314-27)
- 化合物 T11659
- 伊诺加群
- 155415-08-0
- Inogatran (H-314-27)
- H-314-27
- Glycine, N-[(1R)-2-[(2S)-2-[[[3-[(aminoiminomethyl)amino]propyl]amino]carbonyl]-1-piperidinyl]-1-(cyclohexylmethyl)-2-oxoethyl]-
- inogatran