七叶皂苷D
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- CAS号:
- 158800-83-0
- 英文名:
- ESCIN IIB
- 英文别名:
- EscinID;ESCIN IIB;AESCIN IIB; 06035642G6;b-D-Glucopyranosiduronic acid, (3b,4b,16a,21b,22a)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]olean-12-en-3-ylO-b-D-glucopyranosyl-(14)-O-[b-D-xylopyranosyl-(12)]-;β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→4)-O-[β-D-xylopyranosyl-(1→2)]-
- 中文名:
- 七叶皂苷D
- 中文别名:
- 七叶皂苷D;七叶皂苷 IIB
- CBNumber:
- CB62454203
- 分子式:
- C54H84O23
- 分子量:
- 1101.23
- MOL File:
- 158800-83-0.mol
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七叶皂苷D化学性质
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沸点:
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1111.9±65.0 °C(Predicted)
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密度:
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1.45±0.1 g/cm3 (20 ºC 760 Torr)
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酸度系数(pKa):
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2.63±0.70(Predicted)
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七叶皂苷D性质、用途与生产工艺
Escin IIb 是从七叶树种子七叶树中分离出来的，对动物急性炎症有积极作用。Escin IIb 对乙醇诱导的胃粘膜损伤有明显的保护作用。
Escins Ia, Ib, IIa, and IIb (50-200 mg/kg) inhibit the increase of vascular permeability induced by both acetic acid in mice and histamine in rats. Escins Ib, IIa, and IIb (50-200 mg/kg) also inhibit that induced by serotonin in rats, but escin Ia didn't. Escins Ia, Ib, IIa, and IIb (200 mg/kg) inhibit the hind paw edema induced by carrageenin at the first phase in rats. Escin Ia (200 mg/kg) and escins Ib, IIa, and IIb (50-200 mg/kg) inhibit the scratching behavior induced by compound 48/80 in mice, but escin Ia was weakest.
Escin IIb (10-50 mg/kg; p.o.) potently inhibits ethanol-induced gastric mucosal lesions.
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Animal Model:
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Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)
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Dosage:
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P.o.
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Administration:
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10-50 mg/kg
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Result:
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Showed a potent protective effect against ethanol-induced gastric lesions in rats.
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七叶皂苷D
上下游产品信息
上游原料
下游产品
158800-83-0, 七叶皂苷D 相关搜索:
- standardized herbal extract
- reference standards from Chinese medicinal herbs (TCM).
- phytochemical
- pharmaceutical intermediate
- chemical reagent
- 标准品 -中药标准品
- 植物提取物
- 中药对照品
- 对照品
- 标准品
- 七叶皂苷 IIB
- 七叶皂苷D
- 158800-83-0
- EscinID
- β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→4)-O-[β-D-xylopyranosyl-(1→2)]-
- b-D-Glucopyranosiduronic acid, (3b,4b,16a,21b,22a)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]olean-12-en-3-ylO-b-D-glucopyranosyl-(14)-O-[b-D-xylopyranosyl-(12)]-
- 06035642G6
- ESCIN IIB
- AESCIN IIB