钙黄绿素乙酰甲酯
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- CAS号:
- 148504-34-1
- 英文名:
- CALCEIN-AM
- 英文别名:
- CAL-AM;NSC 689290;CALCEIN-AM;AM /Calcein-AM;CALCEIN, AM;CAL-AM;Calcein AM solution;Cellstain- Calcein-AM;Calcein AcetoxyMethyl Ester;-Cellstain-Calcein-AmSolution;Calcein, AM *CAS 148504-34-1*
- 中文名:
- 钙黄绿素乙酰甲酯
- 中文别名:
- 黄绿素-AM;钙黄绿素,AM;钙黄绿素乙酰甲酯;CALCEIN 试剂;钙黄绿素乙酰氧基甲酯;细胞染色剂黄绿素-AM;钙黄绿素-AM/钙黄绿素;钙黄绿素, AM *超级纯*;钙黄绿素-AM CALBIOCHEM;钙黄绿素乙酰甲酯 CALCEIN, AM,≥96.0% (HPLC)
- CBNumber:
- CB6304173
- 分子式:
- C46H46N2O23
- 分子量:
- 994.86
- MOL File:
- 148504-34-1.mol
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钙黄绿素乙酰甲酯化学性质
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熔点:
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>250℃
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沸点:
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982.7±65.0 °C(Predicted)
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密度:
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1.49±0.1 g/cm3(Predicted)
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折射率:
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n20/D 1.479
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闪点:
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85 °C
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储存条件:
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-20°C
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溶解度:
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DMSO: soluble10mg/mL, clear, colorless to slightly yellow
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酸度系数(pKa):
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2.66±0.50(Predicted)
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形态:
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powder
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颜色:
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Colorless
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最大波长(λmax):
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< 300 nm
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生物领域应用:
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Calcium indicators; zinc indicators; cytotoxicity assays; apoptosis assays; viability assays; labile iron pool assays; chemotaxis probes; cell adhesion probes; mitochondrial probes; P-glycoprotein probes;multi-drug resistance probes;treating atherosclerosis,cancer;ischemic disease
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钙黄绿素乙酰甲酯性质、用途与生产工艺
Calcein-AM是用于测定细胞活力的可以渗透细胞的荧光染料。
The calcein-AM dye used to stain the living cells is shown to have a low spontaneousleakage rate less than 15% in 4 hours at 37°C. Dilutions of targets stained by calcein-AM has a linear relationship with measured fluorescence values. NK cells, LAKs, and CTLs are readily detectable by this microtest. Quantitation of killing and kinetic analysis is readily performed with the test system. Calcein-AM is pH independent, better retained and more photostable. In addition, the high level of intracellular retention of calcein-AM and its low-level release after incorporation exclude possible cell-monolayer labeling and allow its use in a cell-cell interaction assay. Moreover, the bright fluorescence can easily be detected and measured by a microplate fluorescence reader. Calcein-AM is a highly lipophilic vital dye that rapidly enters viable cells, is converted by intracellular esterases to calcein that produces an intense green (530-nm) signal, and is retained by cells with intact plasma membrane. From dying or damaged cells with compromised membrane integrity or from cells expressing multidrug resistance protein (MRP), unhydrolyzed substrates and their fluorescent products are rapidly extruded from cells. The calcein-AM assay has been used to assess the cell viability, cytotoxicity and tp quantitate apoptosis.
Calcein-AM is found to be suitable for
in vivo
studies, because it has no deleterious effects on cell function and is, indeed, a marker of cell viability.
钙黄绿素乙酰甲酯
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-D0041 | 钙黄绿素乙酰甲酯
Calcein-AM | 148504-34-1 | 500 μg（2 mg/mL * 250 μL in DMSO） | 2500元 |
| 2024/01/25 | HY-D0041 | 钙黄绿素乙酰甲酯
Calcein-AM | 148504-34-1 | 100 μg（2 mg/mL * 50 μL in DMSO） | 1400元 |
钙黄绿素乙酰甲酯
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全球有 124家供应商
钙黄绿素乙酰甲酯国内生产厂家
148504-34-1, 钙黄绿素乙酰甲酯 相关搜索:
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- Stains&Dyes, A to
- Stains and Dyes
- Fluorescent
- Calcium Probes
- CCalcium Signaling Research Tools
- Xanthene
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Heterocycles
- Fluorescent Labels & Indicators
- Aromatics
- Amines
- 高端化学
- 生化试剂
- 细胞生物学试剂
- 荧光染料
- 荧光探针，标记，颗粒和染色
- C46H46N2O23
- 钙黄绿素乙酰氧基甲酯
- 钙黄绿素-AM CALBIOCHEM
- CALCEIN 试剂
- CALCEIN,AM,≥96.0% (HPLC)用于荧光分析 (1MG 1119.00)
- 钙黄绿素-AM/钙黄绿素
- CELLSTAIN CALCEIN AM SOLUTION(1MM/L DMSO) (3',6'-DI(O-ACETYL)-4',5'-BIS[N,N-BIS(CARBOXYMETHY
- 钙黄绿素乙酰甲酯 CALCEIN, AM,≥96.0% (HPLC)
- Calcein，AM,≥96.0% (HPLC)用于荧光分析 （1mg 1119.00）
- 钙黄绿素乙酰甲酯
- 钙黄绿素, AM *超级纯*
- 细胞染色剂黄绿素-AM
- 黄绿素-AM
- 钙黄绿素,AM
- 148504-34-1
- Tetrakis(acetoxymethyl) 2,2',2'',2'''-(((3',6'-diacetoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylene))bis(azanetriyl))tetraacetate
- AM /Calcein-AM
- Glycine, N,N'-[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, 1,1'-bis[(acetyloxy)methyl] ester
- Calcein-AM (3',6'-Di(O-acetyl)-2',7'-bis[N,N-bis(carboxymethyl)aminomethyl]fluoresceinTetraacetoxymethyl Ester)
- Cellstain Calcein AM Solution(1mM/l DMSO) (3',6'-Di(O-acetyl)-4',5'-bis[N,N-bis(carboxymethy
- Calcein-AM - CAS 148504-34-1 - Calbiochem
- Calcein AM (Calcein acetoxymethyl ester)
- Calcein, AM *UltraPure grade* *CAS 148504-34-1*
- Calcein, AM *CAS 148504-34-1*
- Glycine, N,n0-[[30,60-bis(acetyloxy)-3-oxospiro[
isobenzofuran-1(3h),90-[9h]xanthene]-20,70-diyl]
bis(methylene)]bis[n-[2-[(acetyloxy)methoxy]-2-oxoethyl]-,
bis[(acetyloxy)methyl] Ester
- Calcein O,o0-diacetate Tetrakis(acetoxymethyl)
ester
- calcein o,o'-diacetate tetrakis(acetoxymethyl)ester
- -Cellstain-Calcein-AmSolution
- CALCEIN AM, 4MM IN ANHYDROUS DMSO
- CALCEIN-AM SOLUTION, 1 MMOL IN DMSO*
- Cellstain- Calcein-AM
- 3',6'-DI(O-ACETYL)-2',7'-BIS(N,N-BIS(CARBOXYMETHYL)-AMINOMETHYL)FLUORESCEIN-TETRAACETOXYMETHYL ESTER
- CAL-AM
- CALCEIN-AM
- CALCEIN-ACETOXYMETHYL ESTER, DIACETATE
- NSC 689290
- N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(Methylene)]bis[N-[2-[(acetyloxy)Methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy)
Methyl] Ester
- Calcein AcetoxyMethyl Ester
- Glycine, N,N'-((3',6'-bis(acetyloxy)-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-2',7'-diyl)bis(methylene))bis(N-(2-((acetyloxy)methoxy)-2-oxoethyl)-, bis((acetyloxy)methyl) ester
- 4',5'-Bis(N,N-bis(carboxymethyl)aminomethyl)fluorescein acetoxymethyl ester
- CALCEIN, AM;CAL-AM