利坦丝林
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- CAS号:
- 87051-43-2
- 英文名:
- Ritanserin
- 英文别名:
- R 55667;Tiserton;RITANSERIN;RITANSERIN SEROTONIN ANTAGONIST;6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thia;6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimi;6-[2-[4-[BIS(4-FLUOROPHENYL)-METHYLENE]-1-PIPERIDINYL]-ETHYL]-5H-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE;6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin;6-[2-[4-[Bis(4-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one;6-[2-[4-[Bis(4-fluorophenyl)methylene]piperidin-1-yl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
- 中文名:
- 利坦丝林
- 中文别名:
- 利坦丝林;利坦色林;利坦丝林 25MG;6-(2-(4-(双(4-氟苯基)亚甲基)哌啶-1-基)乙基)-7-甲基-5H-噻唑并[3,2-A]嘧啶-5-酮
- CBNumber:
- CB6458180
- 分子式:
- C27H25F2N3OS
- 分子量:
- 477.57
- MOL File:
- 87051-43-2.mol
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利坦丝林化学性质
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熔点:
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145.5°
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沸点:
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618.7±65.0 °C(Predicted)
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密度:
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1.30±0.1 g/cm3(Predicted)
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储存条件:
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Sealed in dry,2-8°C
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溶解度:
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methanol: >10 mg/mL
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形态:
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solid
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酸度系数(pKa):
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7.74±0.20(Predicted)
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颜色:
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white
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利坦丝林性质、用途与生产工艺
Ritanserin (R 55667) 是一种高效、相对选择性、可口服、长效的 5-HT2 受体拮抗剂，IC50 值为 0.9 nM，对组胺 Histamine H1，多巴胺 Dopamine D2，肾上腺素 Adrenergic α1，Adrenergic α2 受体的活性较弱。
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5-HT
2
Receptor
0.9 nM (IC
50
)
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H
1
Receptor
35 nM (IC
50
)
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D
2
Receptor
70 nM (IC
50
)
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Adrenergic α1
97 nM (IC
50
)
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Adrenergic α2
150 nM (IC
50
)
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Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC
50
of 0.9 nM, less active on Histamine-H
1
(IC
50
, 35 nM), Dopamine-D
2
(IC
50
, 70 nM), Adrenergic-α
1
(IC
50
, 97 nM), Adrenergic-α
2
receptor (IC
50
, 150 nM).
利坦丝林
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-10791 | Ritanserin | | 1 mg | 396元 |
| 2024/01/25 | HY-10791 | 利坦丝林
Ritanserin | 87051-43-2 | 5mg | 990元 |
利坦丝林
生产厂家
全球有 79家供应商
利坦丝林国内生产厂家
87051-43-2, 利坦丝林 相关搜索:
- Serotonin receptor
- API
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Heterocycles
- Aromatics
- C27H25F2N3OS
- 6-(2-(4-(双(4-氟苯基)亚甲基)哌啶-1-基)乙基)-7-甲基-5H-噻唑并[3,2-A]嘧啶-5-酮
- 利坦色林
- 利坦丝林 25MG
- 利坦丝林
- 87051-43-2
- Inhibitor,Histamine Receptor,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,Ritanserin,R-55667,5-HT Receptor,R55667,Beta Receptor,Adrenergic Receptor,Dopamine Receptor
- 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-
- R 55667
- 6-(2-[4-(BIS[4-FLUOROPHENYL]METHYLENE)-1-PIPERIDINYL]ETHYL)-7-METHYL-5H-THIAZOLO(3,2-A)PYRIMIDIN-5-ONE
- 6-[2-[4-[BIS(4-FLUOROPHENYL)-METHYLENE]-1-PIPERIDINYL]-ETHYL]-5H-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE
- RITANSERIN
- 6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimi
- 6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin
- 6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thiazolo[2,3-b]pyriMidin-5-one HCl
- Tiserton
- 6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thia
- 6-[2-[4-[Bis(4-fluorophenyl)methylene]piperidin-1-yl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
- 6-[2-[4-[Bis(4-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one
- RITANSERIN SEROTONIN ANTAGONIST
- 6-[2-[4-(bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one