氢化可的松环戊丙酸酯
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- CAS号:
- 508-99-6
- 英文名:
- HYDROCORTISONE CYPIONATE (200 MG)
- 英文别名:
- Furfural Impurity 9;Hydrocortisone cypiote;Hydrocortisone cipionate;HYDROCORTISONE CYPIONATE;Hydrocortisone 21-cypionate;HYDROCORTISONE CYPIONATE (200 MG);Hydrocortisone Cypionate (1318000);21-(3-Cyclopentyl-1-oxopropoxy)-11β,17α-dihydroxypregn-4-ene-3,20-dione;11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-cyclopentanepropionate;(11β)-21-(3-Cyclopentyl-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione
- 中文名:
- 氢化可的松环戊丙酸酯
- 中文别名:
- 氢化可的松环磷酸酯;氢化可的松杂质23;化合物 T19358;氢化可的松环戊丙酸酯
- CBNumber:
- CB6501660
- 分子式:
- C29H42O6
- 分子量:
- 486.64
- MOL File:
- 508-99-6.mol
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氢化可的松环戊丙酸酯化学性质
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沸点:
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645.0±55.0 °C(Predicted)
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密度:
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1.22±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 125 mg/mL (256.86 mM)
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形态:
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Solid
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酸度系数(pKa):
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12.33±0.70(Predicted)
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颜色:
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White to off-white
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氢化可的松环戊丙酸酯性质、用途与生产工艺
Hydrocortisone cypionate是一种合成的糖皮质激素和皮质类固醇酯。
Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion. Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5. Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation. Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells.
氢化可的松环戊丙酸酯
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更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-U00089 | 氢化可的松环戊丙酸酯 Hydrocortisone cypionate | 508-99-6 | 1mg | 800元 |
2024/08/19 | HY-U00089 | 氢化可的松环戊丙酸酯 Hydrocortisone cypionate | 508-99-6 | 5mg | 1800元 |
508-99-6, 氢化可的松环戊丙酸酯 相关搜索:
- 氢化可的松杂质23
- 化合物 T19358
- 氢化可的松环磷酸酯
- 氢化可的松环戊丙酸酯
- 508-99-6
- Furfural Impurity 9
- Hydrocortisone Cypionate (1318000)
- 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl 3-cyclopentylpropanoate
- Pregn-4-ene-3,20-dione, 21-(3-cyclopentyl-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
- Hydrocortisone cypiote
- HYDROCORTISONE CYPIONATE (200 MG)
- Hydrocortisone cipionate
- (11β)-21-(3-Cyclopentyl-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione
- 21-(3-Cyclopentyl-1-oxopropoxy)-11β,17α-dihydroxypregn-4-ene-3,20-dione
- Hydrocortisone 21-cypionate
- HYDROCORTISONE CYPIONATE
- 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-cyclopentanepropionate