PD 150606
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- CAS号:
- 179528-45-1
- 英文名:
- 3-(4-IODOPHENYL)-2-MERCAPTO-(Z)-2-PROPENOIC ACID
- 英文别名:
- CS-2366;PD 150606;PD150606 (PD 150606;PD150606;PD-150606;PD 150606;(Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid;(Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid;3-(4-IODOPHENYL)-2-MERCAPTO-(Z)-2-PROPENOIC ACID;(Z)-3-(4-IODOPHENYL)-2-SULFANYLPROP-2-ENOIC ACID;(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid;2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-, (2Z)-
- 中文名:
- PD 150606
- 中文别名:
- 非肽CALPAIN抑制剂(PD150606)
- CBNumber:
- CB6767143
- 分子式:
- C9H7IO2S
- 分子量:
- 306.12
- MOL File:
- Mol file
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PD 150606化学性质
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沸点:
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410.4±45.0 °C(Predicted)
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密度:
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1.901±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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DMSO: >20mg/mL
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酸度系数(pKa):
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2.98±0.10(Predicted)
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形态:
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powder
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颜色:
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yellowish
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
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PD 150606性质、用途与生产工艺
PD 150606 是一个选择性的，有细胞渗透性的非肽 calpain 抑制剂，对 μ-calpains 和 m-calpains 作用的 Ki 分别为 0.21 μM 和 0.37 μM，有神经保护活性。
Ki: 0.21 μM (μ-calpains), 0.37 μM (m-calpains)
PD150606 interacts with both calcium-binding domains (μ- and m-calpains) of Calpain.
PD150606 attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices.
PD 150606 (25 μM; 0-12 hours) reduces Cycloheximide (10 mg/ml) -triggered apoptosis of neutrophils.
PD 150606
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-100529 | PD150606 | | 1 mg | 300元 |
| 2024/01/25 | HY-100529 | PD 150606
PD150606 | 179528-45-1 | 5mg | 660元 |
179528-45-1, PD 150606 相关搜索:
- Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
- 细胞生物学试剂
- C9H7IO2S
- 非肽CALPAIN抑制剂(PD150606)
- 179528-45-1
- 2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-, (2Z)-
- (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid
- PD150606 (PD 150606
- CS-2366
- PD150606;PD-150606;PD 150606
- (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid
- (Z)-3-(4-IODOPHENYL)-2-SULFANYLPROP-2-ENOIC ACID
- (2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid
- PD-123319-d6 Bis(Trifluoroacetic Acid Salt) Salt Hydrate
- PD 150606
- 3-(4-IODOPHENYL)-2-MERCAPTO-(Z)-2-PROPENOIC ACID