Alkyne tyramide
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- CAS号:
- 1694495-59-4
- 英文名:
- Alkyne tyramide
- 英文别名:
- Alkyne-phenol;Alkyne tyramide;4-Pentynamide, N-[2-(4-hydroxyphenyl)ethyl]-;Alkyne tyramide,membrane,mitochondria,topology,Inhibitor,inhibit,APEX2,substrate,yeast
- 中文名:
- Alkyne tyramide
- 中文别名:
- 化合物ALKYNE TYRAMIDE
- CBNumber:
- CB68065964
- 分子式:
- C13H15NO2
- 分子量:
- 217.26
- MOL File:
- 1694495-59-4.mol
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Alkyne tyramide化学性质
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沸点:
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464.5±35.0 °C(Predicted)
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密度:
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1.126±0.06 g/cm3(Predicted)
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酸度系数(pKa):
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10.01±0.15(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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Alkyne tyramide性质、用途与生产工艺
Alkyne tyramide 是一种抗坏血酸过氧化物酶 2 (APEX2) 探针。Alkyne tyramide 显著提高了完整酵母细胞的 APEX 标记效率，比 APEX2 底物生物素苯酚 (BP) 具有更大的细胞壁渗透性。Alkyne tyramide 还有助于鉴定 APEX 标记位点，明确线粒体蛋白的膜拓扑的分配。
Yeast cells expressing Su9-APEX2 are incubated with each probe at 2.5 mM final concentration for half an hour, and the labeling reaction is initiated by the addition of 1 mM H2O2. Alkyne tyramide is the most reactive APEX2 substrate for labeling the yeast proteome.
APEX2-mediated Alkyne tyramide labeling in the yeast mitochondria is more effective at probe concentrations above 1 mM.
Alkyne tyramide enables proteomic profiling in the mitochondrial matrix of intact yeast cells with exceptionally high specificity (94%), and offers higher coverage than the traditional APEX2 substrate biotin-phenol (BP).
Alkyne tyramide
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/08/19 | HY-131442 | Alkyne tyramide
Alkyne-phenol | | 5 mg | 333元 |
| 2024/08/19 | HY-131442 | Alkyne-phenol | | 10 mg | 500元 |
1694495-59-4, Alkyne tyramide 相关搜索:
- 化合物ALKYNE TYRAMIDE
- 1694495-59-4
- Alkyne-phenol
- 4-Pentynamide, N-[2-(4-hydroxyphenyl)ethyl]-
- Alkyne tyramide,membrane,mitochondria,topology,Inhibitor,inhibit,APEX2,substrate,yeast
- Alkyne tyramide