网站主页 >> CAS数据库列表 >> 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
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- CAS号:
- 867017-68-3
- 英文名:
- 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
- 英文别名:
- BAY-549;TC-S 7001;Azaindole 1;Azaindole 1 (BAY-549);Rho Kinase Inhibitors;TC-S 7001(Azaindole 1);ROCK-IN-2, 10 mM in DMSO;Azaindole-1 (Rho-kinase inhibitor;RHO-KINASE INHIBITOR;RHO KINASE INHIBITOR;RHO-KINASE INHIBITOR; RHO KINASE INHIBITOR; ROCK
- 中文名:
- 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
- 中文别名:
- BAY-549;化合物AZAINDOLE 1;AZAINDOLE 1游离态;TC-S 7001,ROCK抑制剂;化合物AZAINDOLE 1,10 MM DMSO 溶液;Azaindole 1 (TC-S 7001) 氮杂吲哚 1,S6636;Azaindole 1 (TC-S 7001) 氮杂吲哚 1，S6636;Azaindole-1 (Rho-kinase inhibitor;Rho Kinase Inhibitor);6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺;6-氯-N4-(3,5-二氟-4-((3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧基)苯基)嘧啶-2,4-二胺
- CBNumber:
- CB72510092
- 分子式:
- C18H13ClF2N6O
- 分子量:
- 402.79
- MOL File:
- 867017-68-3.mol
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6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺化学性质
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密度:
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1.61
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储存条件:
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under inert gas (nitrogen or Argon) at 2–8 °C
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溶解度:
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DMSO: Soluble; Ethanol: Soluble
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形态:
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A solid
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酸度系数(pKa):
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13.56±0.40(Predicted)
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颜色:
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Light yellow to yellow
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6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺性质、用途与生产工艺
Azaindole 1 (TC-S 7001) 是一种选择性的ROCK抑制剂，对人ROCK1和ROCK2的ic50分别为0.6 nM和1.1 nM。
| Target | Value |
ROCK1
(Cell-free assay)
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0.6 nM
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ROCK2
(Cell-free assay)
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1.1 nM
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6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/09/19 | S6636 | 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
Azaindole 1 (TC-S 7001) | 867017-68-3 | 2mg | 2211.47元 |
| 2025/09/19 | S6636 | 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
Azaindole 1 (TC-S 7001) | 867017-68-3 | 5mg | 3579.41元 |
6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
生产厂家
867017-68-3, 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺 相关搜索:
- 10mg/4780
- 抑制剂
- 药靶配体
- C18H13ClF2N6O
- Azaindole 1 (TC-S 7001) 氮杂吲哚 1，S6636
- Azaindole-1 (Rho-kinase inhibitor;Rho Kinase Inhibitor)
- Azaindole 1 (TC-S 7001) 氮杂吲哚 1,S6636
- 化合物AZAINDOLE 1,10 MM DMSO 溶液
- 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺/6-氯-N4-(3,5-二氟-4-((3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧基)苯基)嘧啶-2,4-二胺
- TC-S 7001,ROCK抑制剂
- BAY-549
- 6-氯-N4-(3,5-二氟-4-((3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧基)苯基)嘧啶-2,4-二胺
- 化合物AZAINDOLE 1
- AZAINDOLE 1游离态
- 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-B]吡啶-4-基)氧]苯基]-2,4-嘧啶二胺
- 867017-68-3
- Azaindole-1 (Rho-kinase inhibitor
- Azaindole 1 (BAY-549)
- ROCK-IN-2, 10 mM in DMSO
- 6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine , BAY-549
- TC-S 7001(Azaindole 1)
- BAY-549
- inhibit,Rho-kinase,Rho-associated protein kinase,Azaindole-1,ROCKIN2,Rho-associated kinase,Inhibitor,ROCK,ROCK IN 2,Azaindole1,ROK
- 6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine
- 6-chloro-4-N-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]pyrimidine-2,4-diamine
- 2,4-Pyrimidinediamine, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-
- RHO-KINASE INHIBITOR; RHO KINASE INHIBITOR; ROCK
- RHO-KINASE INHIBITOR;RHO KINASE INHIBITOR
- Azaindole 1
- TC-S 7001
- 6-CHLORO-N4-[3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YL)OXY]PHENYL]PYRIMIDIN-2,4-DIAMINE
- Rho Kinase Inhibitors
- 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine