MN 64
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- CAS号:
- 92831-11-3
- 英文名:
- 2-(4-Isopropylpheny)-4H-chroMen-4-one
- 英文别名:
- MN-64;MN64, >98%;MN64; MN 64;2-(4-Isopropyl-phenyl)-chromen-4-one;2-(4-Propan-2-ylphenyl)chromen-4-one;2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]-;MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit;2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist)
- 中文名:
- MN 64
- 中文别名:
- 化合物MN64;TANKYRASES抑制剂(MN-64);2-(4-异丙基苯基)-4H-色烯-4-酮;2-(4-异丙基苯基)-4H-苯并吡喃-4-酮
- CBNumber:
- CB72719624
- 分子式:
- C18H16O2
- 分子量:
- 264.32
- MOL File:
- 92831-11-3.mol
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MN 64化学性质
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熔点:
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63-64 °C(Solv: ethanol (64-17-5))
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沸点:
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389.8±42.0 °C(Predicted)
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密度:
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1.152±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO: soluble20mg/mL, clear
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形态:
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powder
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颜色:
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white to beige
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MN 64性质、用途与生产工艺
MN-64是有效的TNKS1和TNKS2抑制剂，IC50分别为6 nM和72 nM。
| Target | Value |
TNKS1
()
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6 nM
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TNKS2
()
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72 nM
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MN-64 is a potent tankyrase 1 inhibitor, with IC
50
s of 6 nM, 72 nM, 19.1 μM, 39.4 μM for TNKS1, TNKS2, ARTD1 and ARTD2, respectively. MN-64 effectively inhibits Wnt/β-catenin at 1 μM, and blocks STF luciferase activity at 200 nM.
MN 64
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-19351 | MN 64
MN-64 | 92831-11-3 | 5mg | 450元 |
| 2024/01/25 | HY-19351 | MN 64
MN-64 | 92831-11-3 | 10mM * 1mLin DMSO | 495元 |
92831-11-3, MN 64 相关搜索:
- 药靶配体
- 细胞生物学试剂
- 精细化学品
- 药品
- 2-(4-异丙基苯基)-4H-苯并吡喃-4-酮
- 2-(4-异丙基苯基)-4H-色烯-4-酮
- 化合物MN64
- TANKYRASES抑制剂(MN-64)
- 92831-11-3
- MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit
- 2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist)
- MN64; MN 64
- 2-(4-Isopropyl-phenyl)-chromen-4-one
- MN64, >98%
- 4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]-
- 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one
- 2-(4-Isopropylpheny)-4H-chroMen-4-one
- 2-(4-Propan-2-ylphenyl)chromen-4-one
- MN-64