海南冬青苷D
|
|
|
- CAS号:
- 1137648-52-2
- 英文名:
- Ilexhainanoside D
- 英文别名:
- Ilexhainanoside D;Olean-12-ene-23,28-dioic acid, 3,19-dihydroxy-, 28-β-D-glucopyranosyl ester, (3β,4β,19α)-
- 中文名:
- 海南冬青苷D
- 中文别名:
- 海南冬青苷D
- CBNumber:
- CB73158549
- 分子式:
- C36H56O11
- 分子量:
- 664.83
- MOL File:
- 1137648-52-2.mol
|
|
|
海南冬青苷D化学性质
-
沸点:
-
788.1±60.0 °C(Predicted)
-
|
-
密度:
-
1.35±0.1 g/cm3(Predicted)
-
|
-
酸度系数(pKa):
-
4.47±0.70(Predicted)
-
|
海南冬青苷D性质、用途与生产工艺
Ilexhainanoside D 是从 Ilex hainanensis Merr. 中提取的主要三萜皂苷，Ilexhainanoside D 和 Ilexsaponin A1 联合使用后具有抗炎的作用。
The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240 mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of
Firmicutes
/
Bacteroidetes
, reduces the relative abundance of
Desulfovibrio
and increases the relative abundance of
Akkermansia
. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines.
海南冬青苷D
上下游产品信息
上游原料
下游产品
1137648-52-2, 海南冬青苷D 相关搜索:
- 对照品
- 对照品
- 海南冬青苷D
- 1137648-52-2
- Olean-12-ene-23,28-dioic acid, 3,19-dihydroxy-, 28-β-D-glucopyranosyl ester, (3β,4β,19α)-
- Ilexhainanoside D