t-Boc-N-Amido-PEG2-Propargyl
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- CAS号:
- 869310-84-9
- 英文名:
- t-Boc-N-Amido-PEG2-Propargyl
- 英文别名:
- Propargyl-PEG2-NHBoc;Propargyl-PEG3-Boc Amine;t-Boc-N-Amido-PEG2-Propargyl;N-Boc-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine;tert-butyl N-[2-(2-prop-2-ynoxyethoxy)ethyl]carbamate;tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate;Carbamic acid, N-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
- 中文名:
- t-Boc-N-Amido-PEG2-Propargyl
- 中文别名:
- 叔丁氧羰基-PEG2-丙炔;丙炔-二聚乙二醇-氨基叔丁酯;N-BOC-二聚乙二醇-炔丙基;N-叔丁氧羰基-二聚乙二醇-丙炔基;T-BOC-N-酰胺-二聚乙二醇-丙炔;N-BOC-2-[2-(2-丙炔-1-基氧基)乙氧基]乙胺;(2-(2-(丙-2-炔-1-氧基)乙氧基)乙基)氨基甲酸叔丁酯;(2-(2-(2-丙炔基-1-氧基)乙氧基)乙基)氨基甲酸叔丁酯;(2-(2-(丙-2-炔-1-基氧基)乙氧基)乙基)氨基甲酸叔丁酯
- CBNumber:
- CB73364012
- 分子式:
- C12H21NO4
- 分子量:
- 243.3
- MOL File:
- 869310-84-9.mol
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t-Boc-N-Amido-PEG2-Propargyl化学性质
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沸点:
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344.2±27.0 °C(Predicted)
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密度:
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1.033±0.06 g/cm3(Predicted)
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酸度系数(pKa):
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12.22±0.46(Predicted)
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t-Boc-N-Amido-PEG2-Propargyl性质、用途与生产工艺
Propargyl-PEG2-NHBoc 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。Propargyl-PEG2-NHBoc 是一种 PROTAC linker，属于 PEG 类。Propargyl-PEG2-NHBoc 可用于合成一系列 PROTAC 分子。
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Cleavable
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PEGs
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Alkyl/ether
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ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
t-Boc-N-Amido-PEG2-Propargyl
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-118808 | t-Boc-N-Amido-PEG2-Propargyl
Propargyl-PEG2-NHBoc | | 250 mg | 100元 |
| 2024/01/16 | XW0286931084904 | 试剂Propargyl-PEG2-NHBoc
Propargyl-PEG2-NHBoc | | 5g | 1502元 |
t-Boc-N-Amido-PEG2-Propargyl
生产厂家
869310-84-9, t-Boc-N-Amido-PEG2-Propargyl 相关搜索:
- N-BOC-二聚乙二醇-炔丙基
- T-BOC-N-酰胺-二聚乙二醇-丙炔
- N-BOC-2-[2-(2-丙炔-1-基氧基)乙氧基]乙胺
- 叔丁氧羰基-PEG2-丙炔
- (2-(2-(丙-2-炔-1-基氧基)乙氧基)乙基)氨基甲酸叔丁酯
- 丙炔-二聚乙二醇-氨基叔丁酯
- N-叔丁氧羰基-二聚乙二醇-丙炔基
- (2-(2-(丙-2-炔-1-氧基)乙氧基)乙基)氨基甲酸叔丁酯
- (2-(2-(2-丙炔基-1-氧基)乙氧基)乙基)氨基甲酸叔丁酯
- 869310-84-9
- Carbamic acid, N-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
- tert-butyl N-[2-(2-prop-2-ynoxyethoxy)ethyl]carbamate
- Propargyl-PEG3-Boc Amine
- N-Boc-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine
- Propargyl-PEG2-NHBoc
- t-Boc-N-Amido-PEG2-Propargyl
- tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate