钙调神经磷酸酶底物
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- CAS号:
- 113873-67-9
- 英文名:
- ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU
- 英文别名:
- DLDVPIPGRFDRRVSVAAE;[ALA-97]-RII (81-99);CALCINEURIN SUBSTRATE;2: PN: WO2004056970 TABLE;Calcineurin (PP2B) Substrate;Calcineurin phosphatase substrate;Calcineurin Substrate, ≥97% (HPLC);CalcineurinSubstrate,CalcineurinSubstrat;Calcineurin (PP2B) Substrate [DLDVPIPGRFDRRVSVAAE], Non-Phosphorylated;CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED
- 中文名:
- 钙调神经磷酸酶底物
- 中文别名:
- 钙调磷酸酶底物;神经储钙蛋白基质;钙调神经磷酸酶底物;钙调神经磷酸酶底物, ≥97% (HPLC);L-ALPHA-天冬氨酰-L-亮氨酰-L-ALPHA-天冬氨酰-L-缬氨酰-L-脯氨酰-L-异亮氨酰-L-脯氨酰甘氨酰-L-精氨酰-L-苯丙氨酰-L-ALPHA-天冬氨酰-L-精氨酰-L-精氨酰-L-缬氨酰-L-丝氨酰-L-缬氨酰-L-丙氨酰-L-丙氨酰-L-谷氨酸
- CBNumber:
- CB7423431
- 分子式:
- C92H150N28O29
- 分子量:
- 2112.35
- MOL File:
- 113873-67-9.mol
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钙调神经磷酸酶底物化学性质
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密度:
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1.49±0.1 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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形态:
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White powder.
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钙调神经磷酸酶底物性质、用途与生产工艺
钙调神经磷酸酶是哺乳动物脑内含量极丰富的唯一依赖Ca2+及钙调素的磷蛋白磷酸酶。该酶（calcineurin,CaN）在脑外组织如精子细胞、淋巴细胞及肌肉组织中也有分布,但含量远远低于脑。CaN由18kDCa2+结合的调节亚基和61kD钙调素结合的催化亚基组成。除可与Ca2+结合外,该酶还可与Mn2+,Ni2+,Co2+等金属离子结合而影响其活性。
免疫组织化学定位表明，它主要分布在大脑纹状体、海马、大脑皮层等区域，在各个脑区CaN的多种同工酶在特定神经元亚群有不同表达，CaN这种区域性表达可能与不同钙调神经磷酸酶底物专一性有关。
Calcineurin substrate 是来自 cAMP 依赖性蛋白激酶调节性 RII 亚基的多肽。Calcineurin substrate 可用于钙调神经磷酸酶活力的测定。
Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves.
钙调神经磷酸酶底物
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113873-67-9, 钙调神经磷酸酶底物 相关搜索:
- Protein Phosphatase
- Serine/Threonine Phosphatase Substrates
- Serine/Threonine Kinase Biology
- Protein Kinase Related Peptides
- Peptides for Cell Biology
- Protein Kinase SubstratesKinase/Phosphatase Biology
- peptide
- 诊断检测（IVD）
- 对照品
- 多肽
- 细胞生物学
- 细胞信号和神经生物学
- Serine/Threonine Phosphatase Substrates
- Kinase/Phosphatase Biology
- Cell Signaling and Neuroscience
- Cell Biology
- BioChemical
- 钙调神经磷酸酶底物, ≥97% (HPLC)
- 神经储钙蛋白基质
- L-ALPHA-天冬氨酰-L-亮氨酰-L-ALPHA-天冬氨酰-L-缬氨酰-L-脯氨酰-L-异亮氨酰-L-脯氨酰甘氨酰-L-精氨酰-L-苯丙氨酰-L-ALPHA-天冬氨酰-L-精氨酰-L-精氨酰-L-缬氨酰-L-丝氨酰-L-缬氨酰-L-丙氨酰-L-丙氨酰-L-谷氨酸
- 钙调神经磷酸酶底物
- 钙调磷酸酶底物
- 113873-67-9
- ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU USP/EP/BP
- L-Glutamic acid, L-α-aspartyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-L-arginyl-L-arginyl-L-valyl-L-seryl-L-valyl-L-alanyl-L-alanyl-
- Calcineurin Substrate trifluoroacetate salt H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH trifluoroacetate salt
- Calcineurin Substrate, ≥97% (HPLC)
- Calcineurin (PP2B) Substrate
- L-GlutaMic acid, L-a-aspartyl-L-leucyl-L-a-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-a-aspartyl-L-arginyl-L-arginyl-L-valyl-L-seryl-L-valyl-L-alanyl-L-alanyl-
- Calcineurin phosphatase substrate
- CalcineurinSubstrate,CalcineurinSubstrat
- L-alpha-Aspartyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-alpha-aspartyl-L-arginyl-L-arginyl-L-valyl-L-seryl-L-valyl-L-alanyl-L-alanyl-L-glutamic acid
- 2: PN: WO2004056970 TABLE
- Calcineurin (PP2B) Substrate [DLDVPIPGRFDRRVSVAAE], Non-Phosphorylated
- [ALA-97]-RII (81-99)
- H-ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU-OH
- CALCINEURIN SUBSTRATE
- CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED
- DLDVPIPGRFDRRVSVAAE
- ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU