Vasonatrin Peptide (VNP)
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- CAS号:
- 141676-35-9
- 英文名:
- Vasonatrin Peptide (VNP)
- 英文别名:
- Vasonatrin Peptide (VNP);H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH;GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR ((DISULFIDE BRIDGE: CYS6-CYS22);L-Tyrosine, glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (6→22)-disulfide
- 中文名:
- Vasonatrin Peptide (VNP)
- 中文别名:
- 心钠素C型利钠肽嵌合多肽VASONATRIN PEPTIDE (VNP);H-GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH((DISULFIDE BRIDGE: CYS6-CYS22)
- CBNumber:
- CB7998982
- 分子式:
- C124H198N36O36S3
- 分子量:
- 2865.34
- MOL File:
- 141676-35-9.mol
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Vasonatrin Peptide (VNP)
化学性质
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密度:
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1.47±0.1 g/cm3(Predicted)
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Vasonatrin Peptide (VNP)
性质、用途与生产工艺
Vasonatrin peptide (VNP) 是心房钠尿肽 (ANP) 和C型利尿钠肽 (CNP) 的嵌合体，具有高效的静脉扩张和利钠活性。
Natriuretic peptide receptors
Vasonatrin peptide binds with both natriuretic peptide receptor A and B, but with a preference for B. VNP-stimulated cGMP is 11-fold greater in NPRB than NPRA.
The high-fat diet-fed streptozotocin-induced diabetic Sprague-Dawley rats are subjected to ischemia-reperfusion operation. VNP treatment (100 g/kg iv, 10 min before reperfusion) significantly improved the instantaneous first derivation of left ventricle pressure (LV dP/dtmax) and LV systolic pressure and reduced LV end-diastolic pressure, apoptosis index, caspase-3 activity, plasma creatine kinase (CK), and lactate dehydrogenase (LDH) activities. Treatment hypoxia-induced pulmonary hypertension (HPH) with Vasonatrin peptide for 1 week significantly reduceS mean pulmonary arterial pressure, pulmonary vascular resistance, RVH and muscularization of the pulmonary arteries. Acute intravenous administration of 50 microg/kg Vasonatrin peptide significantly ameliorates pulmonary haemodynamics in HPH rats.
Vasonatrin Peptide (VNP)
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2023/03/20 | HY-P1556 | Vasonatrin Peptide (VNP)
Vasonatrin Peptide (VNP) | 141676-35-9 | 500μg | 2000元 |
| 2023/03/20 | HY-P1556 | Vasonatrin Peptide (VNP)
Vasonatrin Peptide (VNP) | 141676-35-9 | 1mg | 3600元 |
Vasonatrin Peptide (VNP)
生产厂家
141676-35-9, Vasonatrin Peptide (VNP)
相关搜索:
- 目录肽
- 目录多肽
- 多肽
- C124H198N36O36S3
- 心钠素C型利钠肽嵌合多肽VASONATRIN PEPTIDE (VNP)
- H-GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH((DISULFIDE BRIDGE: CYS6-CYS22)
- 141676-35-9
- L-Tyrosine, glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (6→22)-disulfide
- Vasonatrin Peptide (VNP)
- H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
- GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR ((DISULFIDE BRIDGE: CYS6-CYS22)