索比尼尔
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- CAS号:
- 68367-52-2
- 英文名:
- Sorbinil
- 英文别名:
- CP-45634;(S)-(+)-Sorbinil;Sorbinil >=98% (HPLC);inhibit,Aldose Reductase,Sorbinil,Inhibitor;(+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione;(4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione;(4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione;(S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;(4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;(4S)-6'-Fluoro-2',3'-dihydrospiro[imidazolidine-4,4'-[4H][1]benzopyran]-2,5-dione
- 中文名:
- 索比尼尔
- 中文别名:
- CBNumber:
- CB81117527
- 分子式:
- C11H9FN2O3
- 分子量:
- 236.2
- MOL File:
- 68367-52-2.mol
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索比尼尔化学性质
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熔点:
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241-243°
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比旋光度:
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D25 +54.0° (c = 1 in methanol)
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密度:
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1.52
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储存条件:
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2-8°C
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溶解度:
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DMSO: ≥20mg/mL
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酸度系数(pKa):
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8.91±0.20(Predicted)
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形态:
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powder
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颜色:
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white to off-white
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旋光性 (optical activity):
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[α]/D +50 to +60°, c = 1 in methanol
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索比尼尔性质、用途与生产工艺
Sorbinil 是一种醛糖还原酶抑制剂 (ARI)。Sorbinil 可用于糖尿病和糖尿病并发症方的研究，降低 AR 活性和抑制多元醇途径，发现它比人类使用的其它 ARI 更安全。
索比尼尔
上下游产品信息
上游原料
下游产品
68367-52-2, 索比尼尔 相关搜索:
- 68367-52-2
- inhibit,Aldose Reductase,Sorbinil,Inhibitor
- Sorbinil >=98% (HPLC)
- (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione
- (+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione
- (S)-(+)-Sorbinil
- (4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione
- CP-45634
- (S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione
- (4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione
- (4S)-6'-Fluoro-2',3'-dihydrospiro[imidazolidine-4,4'-[4H][1]benzopyran]-2,5-dione
- Spiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione, 6-fluoro-2,3-dihydro-, (4S)-