丙二腈
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- CAS号:
- 69567-10-8
- 英文名:
- N-METHYL-1-DEOXYNOJIRIMYCIN
- 英文别名:
- Mednj;N-MDJN;MOR-14;N-Me-DNJ;Aids000354;Aids-000354;N-Methylmoranolin;N-Methylmoranoline;N-METHYLDEOXYNOJIRIMYCIN;DEOXYNOJIRIMYCIN, N-METHYL-
- 中文名:
- 丙二腈
- 中文别名:
- N-甲基脱氧野尻霉素;化合物 T12151;N-甲基-1-脱氧尻霉素;N-甲基-1-脱氧诺吉霉素;N-甲基-1-脱氧野尻霉素;1,5-二脱氧-1,5-亚氨基-1-甲基-D-山梨醇
- CBNumber:
- CB8155656
- 分子式:
- C7H15NO4
- 分子量:
- 177.2
- MOL File:
- 69567-10-8.mol
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丙二腈化学性质
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熔点:
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126-128°C
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沸点:
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367.2±42.0 °C(Predicted)
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密度:
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1.394±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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Methanol (Slightly, Sonicated), Water (Slightly)
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形态:
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Solid
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酸度系数(pKa):
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13.71±0.70(Predicted)
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颜色:
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White to Off-White
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BRN:
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1524564
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稳定性:
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Hygroscopic
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丙二腈性质、用途与生产工艺
N-Methylmoranoline (MOR 14)是 α-glucosidase 的抑制剂。
N-Methylmoranoline dose-dependently decreases the α-1,6-glucosidase activity in rabbit heart extract. The myocardial uptake of a considerable amount of N-Methylmoranoline is sufficient to fully inhibit alpha-1,6-glucosidase. Preischemic treatment with 25, 50, and 100 mg/kg of N-Methylmoranoline dose-dependently reduces the infarct size without altering the blood pressure or heart rate. MOR-14 significantly increases levels of PKC-ε in the particulate fraction at 20 and 30 min of ischaemia and in the cytosolic fraction at 30 min of ischaemia.
N-Methylmoranoline decreases the alpha-1,6-glucosidase activity to approximately 20%, reduces the glycogen breakdown, and attenuates the lactate accumulation at both 10 and 30 minutes of ischemia. MOR-14 is protective against postischemic left ventricular dysfunction through the inhibition of glycogenolysis in the isolated rat heart.
丙二腈
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-U00090 | N-Methylmoranoline | | 1 mg | 1818元 |
| 2024/01/25 | HY-U00090 | 丙二腈
N-Methylmoranoline | 69567-10-8 | 5mg | 4000元 |
丙二腈
生产厂家
全球有 49家供应商
丙二腈国内生产厂家
69567-10-8, 丙二腈 相关搜索:
- Inhibitors
- Glycosidase Inhibitors
- Carbohydrates & Derivatives
- 13C & 2H Sugars
- Antibiotics A to Z
- Antibiotics G-M
- Antibiotics
- BioChemical
- N-甲基-1-脱氧诺吉霉素
- 化合物 T12151
- N-甲基-1-脱氧野尻霉素
- N-甲基-1-脱氧尻霉素
- N-甲基脱氧野尻霉素
- 1,5-二脱氧-1,5-亚氨基-1-甲基-D-山梨醇
- 69567-10-8
- N-Me-DNJ
- NMethylmoranoline,N Methylmoranoline
- N-Methyl-1-deoxynojirimycin, Min. 99%
- N-Methylmoranoline
- N-METHYL-1-DEOXYNOJIRIMYCIN ISO 9001：2015 REACH
- (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-methylpiperidine-3,4,5-triol
- (2R,3R,4R,5S)-2-(HydroxyMethyl)-1-Methyl-3,4,5-piperidinetriol
- N-Methylmoranolin
- Mednj
- Aids-000354
- Aids000354
- 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-methyl-, [2R-(2A,3B,4A,5B)]-
- 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-methyl-, (2R,3R,4R,5S)-
- N-MDJN
- MOR-14
- (2R)-2α-(Hydroxymethyl)-1-methyl-3β,4α,5β-piperidinetriol
- (2R)-1-Methyl-2α-(hydroxymethyl)-3β,4α,5β-piperidinetriol
- DEOXYNOJIRIMYCIN, N-METHYL-
- N-METHYLDEOXYNOJIRIMYCIN
- N-METHYL-1-DEOXYNOJIRIMYCIN
- N-METHYL-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL
- 1,5-DIDEOXY-1,5-IMINO-1-METHYL-D-SORBITOL