瑞舒伐他汀杂质
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- CAS号:
- 854898-53-6
- 英文名:
- Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester)
- 英文别名:
- Rosuvastatin Impurity;Rosuvastatin isomer-23;Rosuvastatin Impurity Q;Rosuvastatin (6S)-Isomer;Rosuvastatin Impurity 6;Rosuvastatin Impurity 107;Rosuvastatin Impurity 050;*Buprenorphine Impurity 19;Rosuvastatin Related Compound 20;Rosuvastatin Related Compound 17
- 中文名:
- 瑞舒伐他汀杂质
- 中文别名:
- 瑞舒伐他汀杂质Q;瑞舒伐他汀杂质 6;瑞舒伐他汀杂质2钠盐;瑞舒伐他汀杂质107;瑞舒伐他汀光降解杂质2;瑞舒中间体1顺式异构体;瑞舒伐他汀5-氧叔丁酯;瑞舒伐他汀对接光降解-2;瑞舒伐他汀3-甲氧基内酯;瑞舒伐他汀相关化合物17
- CBNumber:
- CB82675617
- 分子式:
- C22H28FN3O6S
- 分子量:
- 481.54
- MOL File:
- 854898-53-6.mol
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瑞舒伐他汀杂质化学性质
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沸点:
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719.2±70.0 °C(Predicted)
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密度:
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1.412±0.06 g/cm3(Predicted)
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酸度系数(pKa):
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4.28±0.10(Predicted)
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瑞舒伐他汀杂质性质、用途与生产工艺
瑞舒伐他汀是HMG-CoA还原酶抑制剂，由盐野义(Shionogi)开发为每日一次口服治疗高脂血症。瑞舒伐他汀钙是高效抑制素，其可以比第一代药物更有效地降低LDL-胆固醇和甘油三酯。瑞舒伐他汀杂质为合成瑞舒伐他汀过程中或瑞舒伐他汀储存过程中产生的杂质，瑞舒伐他汀不需要是绝对纯的。绝对纯度是难以达到的理论上的理想。相反地，纯度标准意在确保API不会由于杂质的存在而降低临床使用的安全性。在美国，食品和药物管理局指南建议申请人将一些杂质限制在低于0.1％。
瑞舒伐他汀杂质
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854898-53-6, 瑞舒伐他汀杂质 相关搜索:
- 标准品/对照品/化学试剂/实验
- 杂质对照品
- 杂质
- 对照品-杂质对照品
- 瑞舒伐他汀
- C22H27FN3O6SNa
- (3R,5S)-5-[(6S)-8-氟-4-异丙基-2-(N-甲基甲基磺酰胺基)-5,6-二氢苯并[H]喹唑啉-6-基]-3,5-二羟基戊酸钠盐
- 瑞舒伐他汀杂质94(瑞舒伐丁(6S)-异构体)
- 瑞舒伐他汀杂质107
- 瑞舒伐他汀杂质H019-S-I-12
- 瑞舒伐他汀(6S)-同分异构体钙盐
- 瑞舒伐他汀杂质2钠盐
- 瑞舒伐他汀杂质(5-氧代瑞舒伐他汀叔丁酯)
- 瑞舒伐他汀杂质K(Z式异构体)
- 瑞舒伐他汀钙杂质11(单体)
- 瑞舒伐他汀相关化合物20
- 瑞舒伐他汀相关化合物17
- 瑞舒伐他汀钙盐异构体光降解-8
- 瑞舒伐他汀3-甲氧基脱叉杂质
- 瑞舒伐他汀5-甲氧基脱叉杂质
- 瑞舒伐他汀3-甲氧基内酯
- 瑞舒伐他汀对接光降解-2
- 瑞舒伐他汀钙盐异构体光降解-6
- 瑞舒中间体1顺式异构体
- 瑞舒伐他汀中间体2非对映异构体(3S5S)
- 瑞舒伐他汀中间体2非对映异构体(3S5R)
- 瑞舒伐他汀中间体2非对映异构体(3R5R)
- 瑞舒伐他汀中间体1异构体(4S6R)
- 瑞舒伐他汀Z式异构体叔丁酯
- 瑞舒伐他汀5-氧叔丁酯
- 瑞舒伐他汀杂质 6
- 瑞舒伐他汀杂质Q
- 瑞舒伐他汀G4-2((6S)-ISOMER)
- 瑞舒伐他汀光降解杂质2
- 854898-53-6
- Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester)
- Rosuvastatin Impurity 94(Rosuvastatin (6S)-Isomer)
- *Buprenorphine Impurity 19
- Rosuvastatin 5-Methoxy forked Impurity
- (3RS,5RS,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid
- Rosuvastatin calcium salt isomer photodegradation-6
- (3R,5S)-5-(8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoic AcidQ: What is
(3R,5S)-5-(8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoic Acid Q: What is the CAS Number of
(3R,5S)-5-(8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoic Acid
- (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl
- Benzo[h]quinazoline-6-pentanoic acid, 8-fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, (βR,δS,6S)-
- Rosuvastatin Impurity 107
- Rosuvastatin Related Compound 20
- Rosuvastatin Related Compound 17
- Rosuvastatin isomer-23
- Rosuvastatin Impurity 050
- Rosuvastatin intermediate 1 cis isomer
- Rosuvastatin (6S)-Isomer
- Rosuvastatin Impurity 2 Sodium Salt
- Rosuvastatin Impurity Q
- Rosuvastatin Impurity 6
- sodium (E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethan-3-ylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate
- Rosuvastatin Impurity