6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮
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- CAS号:
- 86672-58-4
- 英文名:
- URB754
- 英文别名:
- URB754;CS-1952;URB754, >=98%;URB754,URB-754;URB754;URB 754;URB-754;6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one;6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one >6-Methyl-2-(p-tolylMino)-4H-benzo[d][1,3]oxazin-4-one;6-Methyl-2-(p-tolylaMino)-4H-benzo[d][1,3]oxazin-4-one;6-Methyl-2-(p-tolylaMino)-1H-benzo[d][1,3]oxazin-4(2H)-one
- 中文名:
- 6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮
- 中文别名:
- 6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮;6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮;6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并恶嗪-4-酮;6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并噁嗪-4-酮;6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮
- CBNumber:
- CB8323934
- 分子式:
- C16H14N2O2
- 分子量:
- 266.3
- MOL File:
- 86672-58-4.mol
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6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮化学性质
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熔点:
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238-240°C
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沸点:
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434.0±48.0 °C(Predicted)
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密度:
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1.23±0.1 g/cm3(Predicted)
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储存条件:
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Refrigerator
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溶解度:
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DMSO (Slightly), Methanol (Slightly, Heated)
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酸度系数(pKa):
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3.76±0.20(Predicted)
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形态:
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Off-white solid.
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颜色:
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White to Off-White
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6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮性质、用途与生产工艺
用途
URB754 is a potent, noncompetitive inhibitor of MGL, exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme. It inhibits rat brain fatty acyl amide hydrolase (FAAH) less effectively with a
n IC50 of 32 μM and binds weakly to the rat CB1 receptor with an IC50 of 3.8 μM. It does not inhibit cyclooxygenase-1 (COX-1) or COX-2 at concentrations up to 100 μM. Inhibition of 2-AG hydrolysis is
associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/16 | M2572 | 6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮
6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one | 86672-58-4 | 10mg | 260元 |
| 2024/01/16 | M2572 | 6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮
6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one | 86672-58-4 | 50mg | 870元 |
6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮
生产厂家
86672-58-4, 6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮 相关搜索:
- Inhibitors
- All Inhibitors
- Chemical for Research
- URB754 is a potent, noncompetitive inhibitor of MGL.
- Research Chemical
- Heterocycles
- Aromatics
- 其它杂环
- 6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并恶嗪-4-酮
- 6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并噁嗪-4-酮
- 6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮
- 6-甲基-2-[(4-甲基苯基)氨基]-4H-3,1-苯并嗪-4-酮
- 6-甲基-2-对甲苯基氨基-4H-3,1-苯并恶嗪-4-酮
- 86672-58-4
- URB754,URB-754
- CS-1952
- URB754;URB 754;URB-754
- 6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one >
- 4H-3,1-Benzoxazin-4-one, 6-methyl-2-[(4-methylphenyl)amino]-
- 6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one
- URB754, >=98%
- 6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one
- 6-Methyl-2-(p-tolylaMino)-4H-benzo[d][1,3]oxazin-4-one
- 6-Methyl-2-(p-tolylaMino)-1H-benzo[d][1,3]oxazin-4(2H)-one
- 6-Methyl-2-(p-tolylMino)-4H-benzo[d][1,3]oxazin-4-one
- 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one
- 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazine-4-one
- URB754