217799-03-6
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- CAS号:
- 217799-03-6
- 英文名:
- KP496
- 英文别名:
- KP496;KP496,KP-496;Benzoic acid, 2-[[[4-[[(4-chlorophenyl)sulfonyl]amino]butyl][[3-[[4-(1-methylethyl)-2-thiazolyl]methoxy]phenyl]methyl]amino]sulfonyl]-
- 中文名:
- 217799-03-6
- 中文别名:
- 化合物 T11764
- CBNumber:
- CB83339666
- 分子式:
- C31H34ClN3O7S3
- 分子量:
- 692.27
- MOL File:
- 217799-03-6.mol
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217799-03-6化学性质
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沸点:
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847.9±75.0 °C(Predicted)
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密度:
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1.378±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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3.09±0.36(Predicted)
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217799-03-6性质、用途与生产工艺
KP49 是一个有选择性的 Leukotriene D4 and Thromboxane A2 受体的双重拮抗剂。
KP496 significantly inhibits acute (day 7) and chronic (day 21) lung inflammation. KP496 attenuates the number of lymphocytes on day 7 and those of macrophages, neutrophils, and eosinophils on days 7 and 21. KP496 and prednisolone significantly suppress the increase of hydroxyl-L-proline content in the lung. Compare to respective vehicle control group, the inhibition ratio of KP496 and prednisolone for increase of hydroxyl-L-proline content is about 74 and 63%, respectively. The KP496 (100 mg/head) group and prednisolone (10 mg/kg) group exhibit significant inhibition of numbers of infiltrating total cells, eosinophils, monocytes/macrophages, and lymphocytes compare with the control group. Infiltration of all types of cells except neutrophils is decreased in the KP496 (30m g/head) group, though not to significant extents.
217799-03-6
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-U00253 | KP496 | | 1 mg | 4500元 |
| 2024/01/25 | HY-U00253 | 217799-03-6
KP496 | 217799-03-6 | 5mg | 8500元 |
217799-03-6, 217799-03-6 相关搜索:
- C31H34ClN3O7S3
- 化合物 T11764
- 217799-03-6
- KP496,KP-496
- Benzoic acid, 2-[[[4-[[(4-chlorophenyl)sulfonyl]amino]butyl][[3-[[4-(1-methylethyl)-2-thiazolyl]methoxy]phenyl]methyl]amino]sulfonyl]-
- KP496