106362-32-7
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- CAS号:
- 106362-32-7
- 英文名:
- ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE
- 英文别名:
- ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE;Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr acetate salt;L-Threonine, L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-;L-Threonine, N-(N-(N2-(N-(N-(N-(N-L-alanyl-L-seryl)-L-thronyl)-L-threonyl)-L-threonyl)-L-asparaginyl)-L-tyrosyl)-
- 中文名:
- 106362-32-7
- 中文别名:
- 肽T;PEPTIDE T;ASTTTNYT;多肽T H-ALA-SER-THR-THR-THR-ASN-TYR-THR-OH
- CBNumber:
- CB8497846
- 分子式:
- C35H55N9O16
- 分子量:
- 857.86
- MOL File:
- 106362-32-7.mol
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106362-32-7化学性质
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沸点:
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1499.5±65.0 °C(Predicted)
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密度:
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1.432±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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3.21±0.10(Predicted)
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106362-32-7性质、用途与生产工艺
Peptide T是源自HIV-1 gp120的V2区的八肽。 Peptide T是 CD4 受体的配体，可阻止 HIV 与CD4受体结合。
Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4. Peptide T at 10
-8
M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10
-9
M concentration significantly inhibits IFN-g production by PBMC.
Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE.
106362-32-7
上下游产品信息
上游原料
下游产品
106362-32-7, 106362-32-7 相关搜索:
- 目录肽
- 多肽
- 目录多肽
- C35H55N9O16
- PEPTIDE T;ASTTTNYT
- 肽T
- 多肽T H-ALA-SER-THR-THR-THR-ASN-TYR-THR-OH
- 106362-32-7
- Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr acetate salt
- L-Threonine, N-(N-(N2-(N-(N-(N-(N-L-alanyl-L-seryl)-L-thronyl)-L-threonyl)-L-threonyl)-L-asparaginyl)-L-tyrosyl)-
- L-Threonine, L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-
- ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE