链丝菌素硫酸盐
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- CAS号:
- 96736-11-7
- 英文名:
- NOURSEOTHRICIN SULFATE
- 英文别名:
- STREPTOTHRICIN;NOURSEOTHRICIN SULFATE;Streptothricin sulfate;NOURSEOTHRICIN SULPHATE;UDVWKDBCMFLRQW-TWRCRAKCSA-N;NOURSEOTHRICIN SULFATE 90+%;nourseothricin,sulfate(salt);Nourseothricin (NTC) Sulfate;Nourseothricin (streptothricin) sulfate;Nourseothricin Sulfate (Streptothricin Sulfate)
- 中文名:
- 链丝菌素硫酸盐
- 中文别名:
- 链丝菌素;诺尔丝菌素;硫酸诺尔丝菌素;链丝菌素硫酸盐;诺尔丝菌素硫酸盐;诺尔丝菌素硫酸盐(链丝菌素硫酸盐);NOURSEOTHRICIN SULFATE 诺尔丝菌素
- CBNumber:
- CB8667052
- 分子式:
- C44H82N18O21S
- 分子量:
- 1231.29488
- MOL File:
- 96736-11-7.mol
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链丝菌素硫酸盐化学性质
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储存条件:
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2-8°C
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溶解度:
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H2O: soluble200mg/mL
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形态:
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solid
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颜色:
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white to light brown
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链丝菌素硫酸盐性质、用途与生产工艺
Nourseothricin sulfate (Streptothricin sulfate) 是一种广谱抗生素，可破坏革兰氏阴性菌的外膜，并且是 Fonsecaea pedrosoi 的主要选择性标记物。Nourseothricin sulfate 抑制原核细胞中蛋白质的生物合成，并强烈抑制真核生物如真菌的生长，还可作为细菌，酵母，丝状真菌和植物细胞等多种生物的选择性标记物。
Escherichia coli
resistance to neurosporin can be sensitive to resistant strains by eliminating their outer membrane resistance. The polycationic antibiotic, Nourseothricin, represents a mixture of several Streptothricins, mainly D and F. Obviously, although very slowly, it can pass the outer membrane via the porin pores. It has been shown earlier that Nourseothricin is able to generate some kind of channels into the outer membrane through which it can pass the cell wall. On the other hand, there are indications that resistant strains containing a Nourseothricin-inactivating acetyl transferase possess an additional protecting system, namely a reduced penetrability of the outer membrane.
Nourseothricin is preferentially excreted via kidney and signs of nephrotoxicity can be observed after its administration. Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions. Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin. There is a high degree of accumulation of Nourseothricin in renal cortical slices. In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation. Age dependent differences in Nourseothricin accumulation does not exist.
链丝菌素硫酸盐
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-129065 | Nourseothricin sulfate | | 1 mg | 250元 |
| 2024/01/25 | HY-129065 | 链丝菌素硫酸盐
Nourseothricin sulfate | 96736-11-7 | 5mg | 500元 |
96736-11-7, 链丝菌素硫酸盐 相关搜索:
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- BioChemical
- Antibiotics
- Antibiotics A to Z
- Antibiotics N-S
- C31H58N12O10C19H34N8O8H2SO4
- C44H82N18O21S
- 链丝菌素
- 诺尔丝菌素硫酸盐(链丝菌素硫酸盐)
- 诺尔丝菌素硫酸盐
- 硫酸诺尔丝菌素
- 诺尔丝菌素
- NOURSEOTHRICIN SULFATE 诺尔丝菌素
- 链丝菌素硫酸盐
- 96736-11-7
- (5ξ)-4-O-Carbamoyl-2-deoxy-2-{[(3S)-3,6-diaminohexanoyl]amino}-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-α-L-lyxo-hexopyranosylamine
- Inhibitor,Streptothricin,Fungal,Nourseothricin sulfate,Bacterial,Antibiotic,Nourseothricin,inhibit
- Nourseothricin (NTC) Sulfate
- Nourseothricin Sulfate (Streptothricin Sulfate)
- [5-[[3-amino-6-(3,6-diaminohexanoylamino)hexanoyl]amino]-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate
- [5-(3,6-diaminohexanoylamino)-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate
- UDVWKDBCMFLRQW-TWRCRAKCSA-N
- NOURSEOTHRICIN SULFATE
- Nourseothricin (streptothricin) sulfate
- Streptothricin sulfate
- NOURSEOTHRICIN SULFATE 90+%
- nourseothricin,sulfate(salt)
- NOURSEOTHRICIN SULPHATE
- STREPTOTHRICIN