化合物SY-640
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- CAS号:
- 168705-70-2
- 英文名:
- Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl-
- 英文别名:
- Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl-;N-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-methylacetamide;Acetamide,inhibit,acnes,Propionibacterium,Endogenous Metabolite,hepatoprotective,Lipopolysaccharide,SY 640,SY640,Inhibitor,SY-640
- 中文名:
- 化合物SY-640
- 中文别名:
- 化合物SY-640;N-(苯并[D][1,3]二氧戊环-5-基甲基)-N-甲基乙酰胺
- CBNumber:
- CB88134163
- 分子式:
- C11H13NO3
- 分子量:
- 207.23
- MOL File:
- 168705-70-2.mol
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化合物SY-640化学性质
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熔点:
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103 °C
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沸点:
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349.2±21.0 °C(Predicted)
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密度:
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1.213±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 100 mg/mL (482.56 mM)
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酸度系数(pKa):
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-0.58±0.70(Predicted)
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形态:
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Liquid
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颜色:
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Light yellow to yellow
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化合物SY-640性质、用途与生产工艺
SY-640 是乙酰胺衍生物，具有有效的保肝作用。SY-640 可减轻痤疮丙酸杆菌和脂多糖诱导的小鼠肝损伤。
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Human Endogenous Metabolite
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SY-640 inhibits the number of liver-infiltrating cells and attenuates the increased expression of leukocyte function-associated antigen-1 on these cells.
SY-640 (Oral; 150 mg/kg; once daily for 7 days) significantly inhibits Propionibacterium acnes and Lipopolysaccharide-induced liver injury, but a single administration is without effect.
SY-640 (p.o.; 150 mg/kg; once daily for three days) significantly increases the liver microsomal cytochrome P-450 content and aminopyrine demethylase activity in mice. The hepatic microsomal aminopyrine demethylase activity is obviously inhibited two hours after oral administration of SY-640.
化合物SY-640
上下游产品信息
上游原料
下游产品
168705-70-2, 化合物SY-640 相关搜索:
- 小分子API
- N-(苯并[D][1,3]二氧戊环-5-基甲基)-N-甲基乙酰胺
- 化合物SY-640
- 168705-70-2
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-methylacetamide
- Acetamide,inhibit,acnes,Propionibacterium,Endogenous Metabolite,hepatoprotective,Lipopolysaccharide,SY 640,SY640,Inhibitor,SY-640
- Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl-