1H-PURINE-2,6-DIONE
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- CAS号:
- 2253744-57-7
- 英文名:
- 1H-Purine-2,6-dione, 7-[[5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-3,7-dihydro-1,3-dimethyl-8-(1-piperazinyl)-, hydrochloride (1:1)
- 英文别名:
- 1H-Purine-2,6-dione, 7-[[5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-3,7-dihydro-1,3-dimethyl-8-(1-piperazinyl)-, hydrochloride (1:1)
- 中文名:
- 1H-PURINE-2,6-DIONE
- 中文别名:
- CBNumber:
- CB89843541
- 分子式:
- C20H21Cl3N8O3
- 分子量:
- 527.79
- MOL File:
- 2253744-57-7.mol
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1H-PURINE-2,6-DIONE化学性质
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溶解度:
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Soluble to 10 mM in water and to 20 mM in DMSO
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1H-PURINE-2,6-DIONE性质、用途与生产工艺
TH5427 hydrochloride 是一种有效的选择性 NUDT5 抑制剂 (IC50=29 nM)。TH5427 hydrochloride 对 NUDT5 的选择性比 MTH1 高 690 倍。TH5427 hydrochloride 阻断乳腺癌细胞孕激素依赖性、PAR 衍生的核 ATP 合成及随后的染色质重塑、基因调控和增殖。
1H-PURINE-2,6-DIONE
上下游产品信息
上游原料
下游产品
2253744-57-7, 1H-PURINE-2,6-DIONE 相关搜索:
- 抑制剂
- C20H21Cl3N8O3
- 2253744-57-7
- 1H-Purine-2,6-dione, 7-[[5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-3,7-dihydro-1,3-dimethyl-8-(1-piperazinyl)-, hydrochloride (1:1)