1,2,3,6-四氢-4-吡啶甲酸盐酸盐
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- CAS号:
- 68547-97-7
- 英文名:
- 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride
- 英文别名:
- IsoguvacineHydrochloride>6-tetrahydro-4-pyridinecarboxylic acid hydrochloride;γ-Aminobutyric acid Receptor,Isoguvacine,GABA Receptor,Gamma-aminobutyric acid Receptor,Isoguvacine hydrochloride,inhibit,Inhibitor
- 中文名:
- 1,2,3,6-四氢-4-吡啶甲酸盐酸盐
- 中文别名:
- 异四氢烟酸;异番石榴碱盐酸盐;异去甲槟榔次碱盐酸盐;1,2,3,6-四氢-4-吡啶羧酸盐酸盐;1,2,3,6-四氢-4-吡啶甲酸盐酸盐
- CBNumber:
- CB91216137
- 分子式:
- C6H9NO2HCl
- 分子量:
- 0
- MOL File:
- 68547-97-7.mol
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1,2,3,6-四氢-4-吡啶甲酸盐酸盐化学性质
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熔点:
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280 °C(dec.)
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储存条件:
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under inert gas (nitrogen or Argon) at 2-8°C
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溶解度:
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H2O: soluble (refrigerate if not used immediately.)
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形态:
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solid
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颜色:
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white
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水溶解性:
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Soluble in water (100mM)
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1,2,3,6-四氢-4-吡啶甲酸盐酸盐性质、用途与生产工艺
Isoguvacine hydrochloride是 GABA 受体激动剂。
Isoguvacine binds to a mouse forebrain synaptic membrane preparation. The specific binding is displaceable by GABA, muscimol and bicuculline but not by picrotoxin or diaminobutyric acid. Kinetic data suggest two binding affinities. Highest levels of binding are observed in the cerebellum, cortex and hippocampus. Isoguvacine binds to membrane preparations of rat forebrain with pharmacological characteristics similar to the postsynaptic GABA recognition site: that it is transported into synaptosomal preparations by an uptake system similar to the high-affinity GABA uptake system; and that recently accumulated isoguvacine is released in a Ca
2+
-dependent manner and by heteroexchange with external GABA. Isoguvacine at a concentration of 50 μM blocks the seizure like events in 2 out of 6 organotypic hippocampal slice cultures. Isoguvacine inhibits the low magnesium induced seizure like events dose dependently.
1,2,3,6-四氢-4-吡啶甲酸盐酸盐
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/16 | I0871 | 异去甲槟榔次碱盐酸盐
Isoguvacine Hydrochloride | 68547-97-7 | 25mg | 250元 |
1,2,3,6-四氢-4-吡啶甲酸盐酸盐
生产厂家
68547-97-7, 1,2,3,6-四氢-4-吡啶甲酸盐酸盐 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Heterocycles
- Amines
- 合成
- 异四氢烟酸
- 异番石榴碱盐酸盐
- 1,2,3,6-四氢-4-吡啶羧酸盐酸盐
- 异去甲槟榔次碱盐酸盐
- 1,2,3,6-四氢-4-吡啶甲酸盐酸盐
- 68547-97-7
- γ-Aminobutyric acid Receptor,Isoguvacine,GABA Receptor,Gamma-aminobutyric acid Receptor,Isoguvacine hydrochloride,inhibit,Inhibitor
- 6-tetrahydro-4-pyridinecarboxylic acid hydrochloride
- IsoguvacineHydrochloride>