(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
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- CAS号:
- 53185-12-9
- 英文名:
- fagomine
- 英文别名:
- fagomine;D-FagoMine;Fagomine, >98%;dextro-fagomine;Fagomine (D-Fagomine);D-Fagomine
(Fagomine);1,2,5-Trideoxy-1,5-epimino-D-xylo-hexitol;(2R)-3β,4α-Dihydroxypiperidine-2α-methanol;(2R)-2-(Hydroxymethyl)piperidine-3β,4α-diol;(2R)-2α-(Hydroxymethyl)piperidine-3β,4α-diol
- 中文名:
- (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
- 中文别名:
- 荞麦碱;桑叶生物碱;荞麦碱, >98%;(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
- CBNumber:
- CB91330549
- 分子式:
- C6H13NO3
- 分子量:
- 147.17
- MOL File:
- 53185-12-9.mol
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(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇化学性质
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熔点:
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185-186℃
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沸点:
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315.4±42.0 °C(Predicted)
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密度:
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1.279
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酸度系数(pKa):
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14.16±0.60(Predicted)
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LogP:
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-0.880 (est)
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(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇性质、用途与生产工艺
Fagomine 是一种温和的糖苷酶 (glycosidase) 抑制剂，Fagomine 作用于 Amyloglucosidase (A.niger)，β-Glucosidase (bovine) 和 Isomaltase (yeast)，Ki 分别为 4.8 μM，39 μM 和 70 μM。
Fagomine (D-fagomine) is an iminosugar that has been shown to selectively agglutinate Enterobacteriales in vitro. Fagomine selectively agglutinates fimbriated enterobacteria (e.g.,
E.coli
) and inhibits their adhesion to the intestinal mucosa; the reason for this is probably related to its structural similarity with lectin-binding saccharides (e.g., mannose). Fagomine is capable of altering this effect of high-fat high-sucrose diet (HFHS) on the proportion of Enterobacteriales and
E.coli
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Fagomine (D-fagomine) is a natural iminosugar that counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales. Compare to the standard group, rats fed high-fat high-sucrose diet (HFHS) with Fagomine (D-fagomine) gain significantly less weight (15.3%) than those fed HFHS (20.9%).
(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-13005 | Fagomine | | 1 mg | 2045元 |
| 2024/01/25 | HY-13005 | (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
Fagomine | 53185-12-9 | 5mg | 4500元 |
(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
生产厂家
53185-12-9, (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇 相关搜索:
- 标准品 -中药标准品
- 对照品
- 植物提取物
- 荞麦碱, >98%
- (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
- 桑叶生物碱
- 荞麦碱
- 53185-12-9
- dextro-fagomine
- D-Fagomine
(Fagomine)
- Fagomine (D-Fagomine)
- Fagomine, >98%
- 3,4-Piperidinediol,2-(hydroxyMethyl)-, (2R,3R,4R)-
- D-FagoMine
- (2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol
- (2R,3R,4R)-3,4-Dihydroxy-2-piperidinemethanol
- 1,2,5-Trideoxy-1,5-epimino-D-xylo-hexitol
- (2R)-3β,4α-Dihydroxypiperidine-2α-methanol
- (2R)-2α-(Hydroxymethyl)piperidine-3β,4α-diol
- (2R)-2-(Hydroxymethyl)piperidine-3β,4α-diol
- fagomine