POLYKETOMYCIN
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- CAS号:
- 200625-47-4
- 英文名:
- polyketomycin
- 英文别名:
- polyketomycin;1,3,7,10,12(2H,4H,5H)-Naphthacenepentone, 4-[[(2S,5S,6R)-5-[[2,6-dideoxy-4-O-(2-hydroxy-3,6-dimethylbenzoyl)-3-C-methyl-α-L-xylo-hexopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-4a,12a-dihydro-4a,11,12a-trihydroxy-2-(1-hydroxyethylidene)-8-methoxy-6-methyl-, (2E,4S,4aR,12aS)-
- 中文名:
- POLYKETOMYCIN
- 中文别名:
- 聚酮霉素;化合物 T12517
- CBNumber:
- CB91359942
- 分子式:
- C44H48O18
- 分子量:
- 864.85
- MOL File:
- 200625-47-4.mol
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POLYKETOMYCIN化学性质
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沸点:
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1032.6±65.0 °C(Predicted)
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密度:
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1.54±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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3.84±0.70(Predicted)
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POLYKETOMYCIN性质、用途与生产工艺
Polyketomycin 是一种从链霉菌属中分离的四环醌糖苷抗生素。Polyketomycin 抑制革兰氏阳性细菌 (Gram-positive bacteria) 的生长，其 MIC 值小于 0.2 µg/mL。Polyketomycin 具有抗菌，抗癌，抗疟疾的作用。
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Traditional Cytotoxic Agents
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Polyketomycin exhibits growth inhibition against L1210 leukemia, EL-4 leukemia, P388 leukemia, Ehrlich carcinoma, IMC carcinoma, colon 26 adnocarcinoma, Meth A fibrosarcoma, FS-3 fibrosarcoma and B16-BL10 melanoma with IC
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values of 3.3 μg/mL, 2.1 μg/mL, 5.2 μg/mL, 1 μg/mL, 0.9 μg/mL, 1.8 μg/mL, 2.4 μg/mL, 1.5 μg/mL and 1.6 μg/mL, respectively.
The acute toxicity (LD
50
, ip) of Polyketomycin in mice is estimated to be 6.25-12.5mg/kg.
POLYKETOMYCIN
上下游产品信息
上游原料
下游产品
200625-47-4, POLYKETOMYCIN 相关搜索:
- C44H48O18
- 聚酮霉素
- 化合物 T12517
- 200625-47-4
- 1,3,7,10,12(2H,4H,5H)-Naphthacenepentone, 4-[[(2S,5S,6R)-5-[[2,6-dideoxy-4-O-(2-hydroxy-3,6-dimethylbenzoyl)-3-C-methyl-α-L-xylo-hexopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-4a,12a-dihydro-4a,11,12a-trihydroxy-2-(1-hydroxyethylidene)-8-methoxy-6-methyl-, (2E,4S,4aR,12aS)-
- polyketomycin