(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺

概述

CAS号:: 1453221-07-2

英文名:: (S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-Indol-3-yl)methyl)-1-amino-15,30-di((S)-sec-butyl)-6-carbamoyl-9,18-bis(3-guanidinopropyl)-1-imino-21,27-diisopropyl-24,35-dimethyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazahexatriacontan-33-yl)-2-((S)-2-amino-3-methylbutanamido)-5-guanidinopentanamide

英文别名:: IDR-1018 (non-amidated);L-Argininamide, L-valyl-L-arginyl-L-leucyl-L-isoleucyl-L-valyl-L-alanyl-L-valyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-;(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-Indol-3-yl)methyl)-1-amino-15,30-di((S)-sec-butyl)-6-carbamoyl-9,18-bis(3-guanidinopropyl)-1-imino-21,27-diisopropyl-24,35-dimethyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazahexatriacontan-33-yl)-2-((S)-2-amino-3-methylbutanamido)-5-guanidinopentanamide

中文名:: (S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺

中文别名:: IDR-1018 (non-amidated);(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺

CBNumber:: CB914630401

分子式:: C71H126N26O12

分子量:: 1535.93

MOL File:: 1453221-07-2.mol

化学性质安全信息用途供应商 5

(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺化学性质

密度:: 1.384±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

酸度系数(pKa):: 13.282±0.46(predicted)

序列:: Val-Arg-Leu-Ile-Val-Ala-Val-Arg-Ile-Trp-Arg-Arg-NH2

安全信息

(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺性质、用途与生产工艺

概述

(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺是一种先天防御调节剂偶联物，对MRSA USA300 LAC、MRSA SAP 0017和S. epidermidis ATCC14990的MIC为16 μg/mL。IDR-1018可用于合成V-IDR1018(万古霉素-先天防御调节剂偶联物)。

(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺上下游产品信息

上游原料

下游产品

(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺生产厂家

全球有 5家供应商 (S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
南昌探真生物技术有限公司	13173652190	pomy@tanzhenbio.com	中国	2395	58
上海毕得医药科技股份有限公司	400-1647117 13681763483	product02@bidepharm.com	中国	62320	58
江西研肽生物医药科技有限公司	13758194781 15083780366	wudegui@tanzhenbio.com	中国	1591	58
江西辐氨生物技术有限公司	18178976185	3855357086@qq.com	中国	1189	58

1453221-07-2, (S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺相关搜索:

IDR-1018 (non-amidated)
(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-吲哚-3-基)甲基)-1-氨基-15,30-二((S)-仲丁基)-6-氨基甲酰基-9,18-双(3-胍基丙基)-1-亚氨基-21,27-二异丙基-24,35-二甲基-8,11,14,17,20,23,26,29,32-九氧代-2,7,10,13,16,19,22,25,28,31-十氮杂三十六烷-33-基)-2-((S)-2-氨基-3-甲基丁酰胺基)-5-胍基戊酰胺
1453221-07-2
IDR-1018 (non-amidated)
L-Argininamide, L-valyl-L-arginyl-L-leucyl-L-isoleucyl-L-valyl-L-alanyl-L-valyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-
(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S,30S,33S)-12-((1H-Indol-3-yl)methyl)-1-amino-15,30-di((S)-sec-butyl)-6-carbamoyl-9,18-bis(3-guanidinopropyl)-1-imino-21,27-diisopropyl-24,35-dimethyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazahexatriacontan-33-yl)-2-((S)-2-amino-3-methylbutanamido)-5-guanidinopentanamide