网站主页 >> CAS数据库列表 >> (S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
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- CAS号:
- 455264-30-9
- 英文名:
- (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
- 英文别名:
- UCB1184197);Zaurategrast ethyl ester;Zaurategrast Ethyl Ester (CDP323;Zaurategrast ethyl ester (Synonyms: CDP323;L-Phenylalanine, N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-, ethyl ester;(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
- 中文名:
- (S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
- 中文别名:
- 化合物 T13388L;(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5;(S)-3-(4-((2,7-萘啶-1-基)氨基)苯基)-2-((2-溴-3-氧代螺〔3.5〕壬-1-烯-1-基基)氨基)丙酸甲酯
- CBNumber:
- CB92623655
- 分子式:
- C28H29BrN4O3
- 分子量:
- 549.46
- MOL File:
- 455264-30-9.mol
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(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5化学性质
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熔点:
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192.5-195 °C
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沸点:
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698.2±55.0 °C(Predicted)
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密度:
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1.44±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 150 mg/mL (273.00 mM); Water: < 0.1 mg/mL (insoluble)
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酸度系数(pKa):
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4.84±0.30(Predicted)
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(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5性质、用途与生产工艺
Zaurategrast ethyl ester (CDP323) 是 CT7758 的乙酯前药，是 α4β1/α4β7 整联蛋白拮抗剂，可用于炎症和自身免疫疾病的研究。
Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer.
(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-75385 | Zaurategrast ethyl ester | | 1 mg | 1400元 |
| 2024/04/30 | HY-75385 | (S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
Zaurategrast ethyl ester | 455264-30-9 | 5mg | 3500元 |
(S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
生产厂家
455264-30-9, (S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5 相关搜索:
- 化合物 T13388L
- (S)-3-(4-((2,7-萘啶-1-基)氨基)苯基)-2-((2-溴-3-氧代螺〔3.5〕壬-1-烯-1-基基)氨基)丙酸甲酯
- (S)-3-(4 - ((2,7-萘啶-1-基)氨基)苯基)-2 - ((2-溴-3-氧代螺〔3.5
- 455264-30-9
- L-Phenylalanine, N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-, ethyl ester
- Zaurategrast ethyl ester
- Zaurategrast Ethyl Ester (CDP323
- Zaurategrast ethyl ester (Synonyms: CDP323
- UCB1184197)
- (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate