CALIMYCIN 半镁盐
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- CAS号:
- 72124-77-7
- 英文名:
- CALCIMYCIN A23187 HEMIMAGNESIUM SALT
- 英文别名:
- Calcimycin hemimagnesium;a23187hemimagnesium salt;CALCIMYCIN HEMIMAGNESIUM SALT;CALCIMYCIN A23187 HEMIMAGNESIUM SALT;calcium ionophore A23187 hemimagnesium;CALCIUM IONOPHORE A23187 HEMIMAGNESIUM SALT;CALCIUM IONOPHORE A23187 HEMIMAGNESIUM SALT BIOCHEMIKA;A23187 hemimagnesium salt, Antibiotic A 23187 hemimagnesium salt, Calcimycin hemimagnesium salt, Calimycin hemimagnesium salt
- 中文名:
- CALIMYCIN 半镁盐
- 中文别名:
- CALIMYCIN 半镁盐
- CBNumber:
- CB9367461
- 分子式:
- C58H72MgN6O12
- 分子量:
- 1069.55
- MOL File:
- 72124-77-7.mol
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CALIMYCIN 半镁盐化学性质
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储存条件:
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2-8°C
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溶解度:
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acetone: 5 mg/mL, clear, faintly yellow
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BRN:
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6765085
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CALIMYCIN 半镁盐性质、用途与生产工艺
Calcimycin (A-23187) hemimagnesium 是一种抗生素和独特的二价阳离子离子载体 (divalent cation ionophore)，如钙离子和镁离子。Calcimycin hemimagnesium 通过增加细胞内钙浓度诱导 Ca2+ 依赖性细胞死亡。Calcimycin hemimagnesium 抑制革兰氏阳性细菌和一些真菌的生长，还抑制 ATP 酶的活性并解耦哺乳动物细胞的氧化磷酸化 (OXPHOS)，诱导细胞凋亡 (apoptosis)。
Calcimycin (A-23187) hemimagnesium mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner.
Calcimycin (A-23187) hemimagnesium (2.5 or 7.5 nM; intrapleurally) induces protein leakage.
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Animal Model:
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Mice (ICR, 25-30 g)
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Dosage:
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2.5 or 7.5 nM
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Administration:
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Intrapleurally
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Result:
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Two hours after 2.5 nM, or three hours after 7.5 nM, challenge the protein levels in the pleural cavity were equivalent to about a half of their corresponding peak values.
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CALIMYCIN 半镁盐
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2023/03/20 | HY-N6687B | CALIMYCIN 半镁盐
Calcimycin hemimagnesium | 72124-77-7 | 1mg | 2600元 |
| 2023/03/20 | HY-N6687B | CALIMYCIN 半镁盐
Calcimycin hemimagnesium | 72124-77-7 | 5mg | 7200元 |
72124-77-7, CALIMYCIN 半镁盐 相关搜索:
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- Antibiotics
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- C29H36Mg05N3O6
- CALIMYCIN 半镁盐
- 72124-77-7
- Calcimycin hemimagnesium
- A23187 hemimagnesium salt, Antibiotic A 23187 hemimagnesium salt, Calcimycin hemimagnesium salt, Calimycin hemimagnesium salt
- a23187hemimagnesium salt
- CALCIUM IONOPHORE A23187 HEMIMAGNESIUM SALT BIOCHEMIKA
- calcium ionophore A23187 hemimagnesium
- CALCIUM IONOPHORE A23187 HEMIMAGNESIUM SALT
- CALCIMYCIN HEMIMAGNESIUM SALT
- CALCIMYCIN A23187 HEMIMAGNESIUM SALT