Cyclosporin A-Derivative 1 Free base
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- CAS号:
- 286852-20-8
- 英文名:
- Cyclosporin A-Derivative 1 Free base
- 英文别名:
- Cyclosporin A-Derivative 1 Free base;N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-;Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
- 中文名:
- Cyclosporin A-Derivative 1 Free base
- 中文别名:
- CBNumber:
- CB94844681
- 分子式:
- C65H117N11O14
- 分子量:
- 1276.69
- MOL File:
- 286852-20-8.mol
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Cyclosporin A-Derivative 1 Free base化学性质
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沸点:
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1225.9±65.0 °C(Predicted)
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密度:
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1.093±0.06 g/cm3(Predicted)
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溶解度:
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DCM, Methanol
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形态:
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Solid
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酸度系数(pKa):
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13.07±0.46(Predicted)
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颜色:
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Off-White
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Cyclosporin A-Derivative 1 Free base性质、用途与生产工艺
Cyclosporin A-Derivative 1 (Free base) 是环孢菌素 A 衍生的结晶中间体，来自专利 WO 2013167703 A1。Cyclosporin A 是一种免疫抑制剂，能够与亲环蛋白结合并抑制钙调磷酸酶。
Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporin A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate.
Cyclosporin A-Derivative 1 Free base
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-P1355A | Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base | 286852-20-8 | 1mg | 1500元 |
| 2024/01/25 | HY-P1355A | Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base | 286852-20-8 | 5mg | 3500元 |
Cyclosporin A-Derivative 1 Free base
生产厂家
286852-20-8, Cyclosporin A-Derivative 1 Free base 相关搜索:
- 286852-20-8
- Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
- N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-
- Cyclosporin A-Derivative 1 Free base