Exendin-3 (9-39) amide

Exendin-3 (9-39) amide Struktur
133514-43-9
CAS-Nr.
133514-43-9
Englisch Name:
Exendin-3 (9-39) amide
Synonyma:
EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
CBNumber:
CB0109941
Summenformel:
C149H234N40O47S
Molgewicht:
3369.76
MOL-Datei:
133514-43-9.mol

Exendin-3 (9-39) amide Eigenschaften

Dichte
1.51
RTECS-Nr.
LF2460000
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Löslichkeit
H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
Aggregatzustand
Solid
Wasserlöslichkeit
Soluble in water at 1mg/ml
InChIKey
WSEVKKHALHSUMB-UHFFFAOYSA-N

Sicherheit

WGK Germany  3

Exendin-3 (9-39) amide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.

Verwenden

Biological probe.

Allgemeine Beschreibung

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.

Exendin-3 (9-39) amide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Exendin-3 (9-39) amide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • EXENDIN 3 (9-39)
  • EXENDIN-3 (9-39) AMIDE
  • EXENDIN (9-39)
  • EXENDIN (9-39) AMIDE
  • EXENDIN [9-39] PEPTIDE
  • EXENDIN FRAGMENT 9-39
  • DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
  • M.W. 3369.79 C149H234N40O47S
  • ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
  • Exendin 3 (heloderma horridum), 1-de-L-histidine-2-de-L-serine-3-de-L-aspartic acid-4-deglycine-5-de-L-threonine-6-de-L-phenylalanine-7-de-L-threonine-8-de-L-serine-
  • 9-39-Exendin 3(Heloderma horridum)
  • EXENDIN FRAGMENT 9-39;EXENDIN (9-39)
  • H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
  • Exendin FragMent 9-39Exendin
  • H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt
  • 9-39-Exendin 3(Heloderma horridum) (9CI)
  • Exendin (9-39) Acetate
  • Exendin 4 (9-39) amide
  • Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRp-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2, ≥95%(HPLC)
  • L-Serinamide, L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-p...
  • Exendin Fragment 9-39 >=95% (HPLC)
  • Exendin-3 (9-39) amide USP/EP/BP
  • GCGR,Glucagon Receptor,Avexitide,Inhibitor,inhibit
  • Exendin-3 (9-39) amide/Avexitide
  • Hexanal Impurity 5
  • Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TR|p|-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • Exendin-4 (9-39)
  • 133514-43-9
  • C149H234N40O47S
  • C149H234N40O47S1
  • Hormones
  • Obesity Research
  • Exendin
  • Cytokines, Growth Factors and Hormones
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Peptide
  • GLP-1 Receptor LigandsObesity Research
  • Cytokines Growth Factors and Hormones (Obesity)
  • ExendinPeptides for Cell Biology
  • Hormones
  • Obesity Peptides
  • Obesity Research
  • Other Obesity Research Products
  • Glucagon receptor and related
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