(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid
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- CAS-Nr.
- 547-98-8
- Englisch Name:
- (3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid
- Synonyma:
- THCA;Coprocholic acid;Trihydroxycholestanoic acid;3α,7α,12α-Trihydroxycoprostanic Acid;3α,7α,12α-Trihydroxycoprostanoic acid;3,7,12-trihydroxycholestan-26-oic acid;3α,7α,12α-Trihydroxy-5β-cholestanoic acid;3α,7α,12α-Trihydroxy-5β-cholestan-27-oic acid;3α,7α,12α-Trihydroxy-5β-cholestan-26-oic acid;(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid
- CBNumber:
- CB01235764
- Summenformel:
- C27H46O5
- Molgewicht:
- 450.65
- MOL-Datei:
- 547-98-8.mol
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(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid Eigenschaften
- storage temp.
- -20°C
- Löslichkeit
- Chloroform (Slightly, Heated), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
3α,7α,12α-Trihydroxycoprostanic Acid is a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α,12α-Trihydroxycoprostanic Acid.
Definition
ChEBI: A steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions.
Allgemeine Beschreibung
Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.
(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 9)Lieferanten
- (3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid
- 3α,7α,12α-Trihydroxy-5β-cholestan-26-oic acid
- 3α,7α,12α-Trihydroxy-5β-cholestan-27-oic acid
- 3α,7α,12α-Trihydroxy-5β-cholestanoic acid
- 3α,7α,12α-Trihydroxycoprostanoic acid
- THCA
- Trihydroxycholestanoic acid
- 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
- Coprocholic acid
- 3,7,12-trihydroxycholestan-26-oic acid
- Cholestan-26-oic acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-
- 3α,7α,12α-Trihydroxycoprostanic Acid
- 547-98-8
