Venlafaxine hydrochloride

Venlafaxine hydrochloride  Struktur
99300-78-4
CAS-Nr.
99300-78-4
Englisch Name:
Venlafaxine hydrochloride
Synonyma:
VENLAFAXINE HCL;EFFEXOR;D,L-VENLAFAXINE;D,L-VENLAFAXINE, HYDROCHLORIDE;Vexor;Venlift;AKOS 92111;VENLAFAXINEHCL;Venlaffaxine HCL;Venlafaxine HCL API
CBNumber:
CB0136181
Summenformel:
C17H28ClNO2
Molgewicht:
313.86
MOL-Datei:
99300-78-4.mol

Venlafaxine hydrochloride Eigenschaften

Schmelzpunkt:
207-209°C
Flammpunkt:
9℃
storage temp. 
2-8°C
Löslichkeit
H2O: >10mg/mL
Aggregatzustand
powder
Farbe
white
Merck 
14,9946
BCS Class
1
InChIKey
QYRYFNHXARDNFZ-UHFFFAOYSA-N
CAS Datenbank
99300-78-4(CAS DataBase Reference)
EPA chemische Informationen
Cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, hydrochloride (1:1 (99300-78-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi,T,F
R-Sätze: 36/37/38-36-39/23/24/25-23/24/25-11
S-Sätze: 26-37/39-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS-Nr. GV8872760
HS Code  29225090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H411 Giftig für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gewässergefährdend Kategorie 2
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P391 Verschüttete Mengen aufnehmen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Venlafaxine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Venlafaxine hydrochloride, a novel phenethylamine derivative, was introduced in the U.S.A. as an antidepressant. Venlafaxine is reported to be the first in the class of the second-generation of antidepressants with dual serotonidnorepinephrine reuptake inhibitory activity. Venlafaxine lacks any affinity for muscarinic, cholinergic, histaminergic and noradrenergic receptors and therefore, has an unusually favorable side effect profile compared with classical tricyclic antidepressants and shows less cardiotoxicity. In addition, venlafaxine has a rapid onset of action that makes it unique among the antidepressant agents. Other indications for venlafaxine include the treatment of obsessive and panic disorders, and obesity. Both enantiomers of venlafaxine were reported to have similar biological activity.

Chemische Eigenschaften

White Crystalline Powder

Verwenden

A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant

Allgemeine Beschreibung

A Certified Snap-N-Spike? Solution suitable for many LC/MS and GC/MS applications from forensic or clinical toxicology analysis to urine drug testing. Also known by the brand name Effexor?, venlafaxine is an SNRI antidepressant approved for the treatment of major depressive and general anxiety disorders.

Biologische Aktivität

Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (K i values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

Venlafaxine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Venlafaxine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 631)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5993 58
Anhui Yiao New Material Technology Co., Ltd
+86-199-55145978 +8619955145978
sales8@anhuiyiao.com China 253 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 994 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3012 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763
info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2931 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282
alice@crovellbio.com China 8822 58

99300-78-4()Verwandte Suche:


  • AKOS 92111
  • Effexor hydrochloride
  • Wy 45030 hydrochloride
  • (rs)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
  • VENLAFAXINE HYDROCHLORIDE
  • 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-cyclohexanohydrochloride
  • VENLAFAXINE HCI, 99%
  • VenlfaxineHydrochloride
  • Venlafaxinehydrochloride/VenlafaxineHCl
  • N,N-dimethyl-2-p-methoxyphenyl-2-(1-hydroxycyclohexyl) ethylamine hydrochloride
  • VENLAFAXINEHCL
  • 1-[2-DIMETHYL AMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANONE HYDROCHLORIDE (+)
  • Venlaffaxine HCL
  • Venlafaxine hydrochloride,(+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
  • Venlafaxine Hydrochloride (100 mg)
  • Venlafaxine hydrochloride solution
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL, HCL
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL HYDROCHLORIDE
  • 1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL
  • (+/-)-1-(alpha-((dimethylamino)methyl)-p-methoxybenzyl)cyclohexanol hydrochloride
  • 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-1-cyclohexanol hydrochloride
  • Venlafaxine hydrochloride CRS
  • Venlafaxine hydrochloride solution in Methanol, 100μg/mL
  • VENLAFAXINE HCL PELLETS 33%
  • Venlafaxine hydrochloride USP/EP/BP
  • Venlafaxine HCl (Wy 45030 HCl)
  • Venlafaxine for system suitability (Y0000588)Q: What is Venlafaxine for system suitability (Y0000588) Q: What is the CAS Number of Venlafaxine for system suitability (Y0000588)
  • Venlafaxine hydrochloride (Y0000587)
  • Venlafaxine HydrochlorideQ: What is Venlafaxine Hydrochloride Q: What is the CAS Number of Venlafaxine Hydrochloride Q: What is the storage condition of Venlafaxine Hydrochloride
  • Venlafaxine Hydrochloride (1711268)
  • Venlift
  • Vexor
  • Venlafaxine hydrochloride, 98%, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI)
  • Venlafaxine (hydrochloride) (CRM)
  • VENLAFAXINE HCL
  • EFFEXOR
  • D,L-VENLAFAXINE
  • D,L-VENLAFAXINE, HYDROCHLORIDE
  • Venlafaxine HCL API
  • Venlafaxine HCl 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
  • Venlafaxine Hydrochloride (non sterile)
  • Venelafaxine Reference Standard
  • 99300-78-4
  • 00-00-2
  • 9300-78-4
  • C17H27NO2.HCl
  • C17H27NO2
  • C17H28ClNO2
  • C17H27NO2HClC17H28ClNO2
  • C17H27NO2ClH
  • Serotonin receptor
  • APIs
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Antidepressant
  • Active Pharmaceutical Ingredients
  • Medicine intermediate
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