Canrenon
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- CAS-Nr.
- 976-71-6
- Bezeichnung:
- Canrenon
- Englisch Name:
- Canrenone
- Synonyma:
- CANRENONE-D4;sc9376;11614r.p;RP-11614;CANRENONE;phanurane;ALDADIENE;kanlitong;NSC 261713;Canrenone CRS
- CBNumber:
- CB0147626
- Summenformel:
- C22H28O3
- Molgewicht:
- 340.46
- MOL-Datei:
- 976-71-6.mol
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Canrenon Eigenschaften
- Schmelzpunkt:
- 158-1600C
- alpha
- D +24.5° (chloroform)
- Siedepunkt:
- 416.25°C (rough estimate)
- Dichte
- 1.1236 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- room temp
- Löslichkeit
- DMSO: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- Optische Aktivität
- [α]/D +17 to +24°, c = 1 in chloroform-d
- Wasserlöslichkeit
- 272.4ug/L(25 ºC)
- InChI
- InChI=1/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/s3
- InChIKey
- UJVLDDZCTMKXJK-MUWITHSMNA-N
- SMILES
- [C@@]12(CCC(=O)O1)CC[C@@]1([H])[C@]3([H])C=CC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]21C |&1:0,8,10,20,22,26,r|
- LogP
- 2.54 at 25℃
- CAS Datenbank
- 976-71-6
- NIST chemische Informationen
- Canrenone(976-71-6)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn,N |
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| R-Sätze: |
40-51/53 |
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| S-Sätze: |
36/37-61 |
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| RIDADR |
UN 3077 9 / PGIII |
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| WGK Germany |
3 |
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| HS Code |
29329990 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenität |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
| H411 |
Giftig für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 2 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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Canrenon Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale yellow to pale Green Solid
Verwenden
Aldosterone antagonist. Diuretic
Weltgesundheitsorganisation (WHO)
Canrenone, which has aldosterone antagonist activity, is a major
metabolite of spironolactone and the major metabolite of potassium canrenoate.
See WHO comments for potassium canrenoate and spironolactone.
Biologische Aktivität
Mineralocorticoid receptor antagonist. Active metabolite of spironolactone ((7a,17a)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid g-lactone ).
Canrenon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Canrenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 254)Lieferanten
976-71-6(Canrenon)Verwandte Suche:
- phanurane
- pregna-4,6-diene-21-carboxylicacid,17-hydroxy-3-oxo-,gamma-lactone,(17-alph
- sc9376
- spirolactonesc14266
- CANRENOIC ACID GAMMA LACTONE
- CANRENONE
- 4,6-ANDROSTADIEN[(17(B-1')-SPIRO-5')]-PERHYDROFURAN-2,3-DIONE
- 4,6-ANDROSTEN-17-ALPHA-YL-PROPIONIOACID-R-LACTONE
- PREGNA-4,6-DIENE-17-BETA-0L-3-ONE-21-CARBOXYLIC ACID-GAMMA LACTONE
- 11614r.p
- 17-(2-Carboxyethyl)17-hydroxy-3-oxoandrosta-4,6-dienelactone
- 17-(2-Carboxyethyl)17-hydroxyandrosta-4,6-dien-3-onelactone
- 17-hydroxy-3-oxo-,gamma-lactone,(17-alpha)-pregna-6-diene-21-carboxylicacid
- 17-Hydroxy-3-oxo-17-pregna-4,6-diene-21-carboxylicacid-lactone
- ALDADIENE
- 17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid gamma-lactone
- CANRENONE[SPIRONOLACTONE INTERMEDIATE]
- Canrenone98.5%Min
- 17a-(2-Carboxyethyl-17b-hydroxyandrosta-4,6-dien-3-one Lactone
- (7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid g-Lactone
- ((7 )-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid -Lactone)
- (7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid -Lactone
- 17a-2-Carboxyethyl-17-hydroxyandrosta-4,6-dien-3-one Lactone
- Journal of risperidone
- Canrenone, >=97%
- (17R)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid γ-lactone
- (17R)-3-Oxo-17-hydroxypregna-4,6-diene-21-carboxylic acid γ-lactone
- (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylicacidγ-lactone
- Spironolactone Related Compound A (100 mg) (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (AS)
- Eplerenone IMpurity - Canrenone
- (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
- Spironolactone Related CoMpound A
- Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)-
- Canrenone
17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid gamma-lactone
- NSC 261713
- 7-Carboxy-9(11)&Delta
- kanlitong
- Spironolactone Impurity 6（Spironolactone EP Impurity F）
- Spironolactone EP Impurity F
- Eplerenone Impurity 28
- 10,13-Dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
- Canrenone Solution, 100ppm
- Eplerenone Canrenone Impurity
- Canrenone CRS
- 6,7-Dehydro-7α-desthioacetylspironolactone
- RP-11614
- Spironolactone EP Impurity F-d4 (Canrenone-d4)
- Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, (17α)-
- Spironolactone EP Impurity F (Canrenone)
- 7-Carboxy-9(11)Δ-canrenone
- Spiranolactone Impurity F
- Canrenone D7Q: What is
Canrenone D7 Q: What is the CAS Number of
Canrenone D7 Q: What is the storage condition of
Canrenone D7 Q: What are the applications of
Canrenone D7
- CanrenoneQ: What is
Canrenone Q: What is the CAS Number of
Canrenone Q: What is the storage condition of
Canrenone Q: What are the applications of
Canrenone
- Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017)
- CANRENONE-D4
- Candy, ketone
- 6,7-Dehydro-7α-desthioacetylspironolactone
- Spironolactone USP Related Compound A
