enniatin A

enniatin A Struktur
2503-13-1
CAS-Nr.
2503-13-1
Englisch Name:
enniatin A
Synonyma:
enniatin A;Lateritin I;N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-);(3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
CBNumber:
CB02079105
Summenformel:
C36H63N3O9
Molgewicht:
681.906
MOL-Datei:
2503-13-1.mol

enniatin A Eigenschaften

Schmelzpunkt:
122-124 °C
Siedepunkt:
847.4±65.0 °C(Predicted)
Dichte
1.022±0.06 g/cm3(Predicted)
storage temp. 
-20°C
Löslichkeit
DMSO: soluble10mg/mL
Aggregatzustand
White to off-white crystalline solid.
pka
-0.96±0.70(Predicted)

Sicherheit

Kennzeichnung gefährlicher T
R-Sätze: 23/24/25
S-Sätze: 45
RIDADR  2811
WGK Germany  3
HazardClass  6.1(a)
PackingGroup  I
HS Code  2934999090

enniatin A Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines. Many function as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin A is one of four major analogs in the enniatin complex . It has been shown to moderately inhibit acyl-CoA:cholesterol acyltranferase activity in rat liver microsomes with an IC50 value of 22 μM. Enniatin A also demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa.

Verwenden

Enniatins are a family of depsipeptide ionophores, produced by several Fusarium species. More recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A is one of four major analogues of the enniatin complex and has not previously been available for investigation.

Definition

ChEBI: An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-isoleucine units.

enniatin A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


enniatin A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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laboratory@coreychem.com China 30255 58
BOC Sciences
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inquiry@bocsci.com United States 19743 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9709 58
Lynnchem 86-(0)29-85992781 17792393971
info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
info@novachemistry.com United Kingdom 4381 58
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012
sales@regentsciences.com China 9288 58

2503-13-1()Verwandte Suche:


  • enniatin A
  • N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-)
  • Lateritin I
  • Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
  • (3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
  • 2503-13-1
  • C36H63N3O9
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