Fluvastatin sodium salt
|
|
|
- CAS-Nr.
- 93957-55-2
- Englisch Name:
- Fluvastatin sodium salt
- Synonyma:
- FLUVASTATIN;FLUVASTATIN SODIUM;Flurastatin Sodium;Fluvastatin sodium hydrate;xu62-320;3-cs/ex-PinD;fluindostatin;FLUVASTATIN NA;(+)-Pinanediol;XU 62320 sodium
- CBNumber:
- CB0231286
- Summenformel:
- C24H25FNNaO4
- Molgewicht:
- 433.45
- MOL-Datei:
- 93957-55-2.mol
|
Fluvastatin sodium salt Eigenschaften
- Schmelzpunkt:
- 194-197°C
- storage temp.
- 2-8°C
- Löslichkeit
- H2O: ≥9mg/mL
- Aggregatzustand
- powder
- Farbe
- white to tan
- Merck
- 14,4218
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
- InChIKey
- ZGGHKIMDNBDHJB-RPQBTBOMSA-M
- CAS Datenbank
- 93957-55-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
MJ9675050 |
|
|
| HS Code |
2933995300 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
|
Fluvastatin sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Fluvastatin sodium is the fourth HMG-CoA reductase inhibitor to reach the market
as a dietary adjunct for lowing total and low-density lipoprotein (LDL) cholesterol.
Fluvastatin sodium is the first totally synthetic inhibitor of its class and has more
potent effects on reducing serum total and LDL cholesterol and serum triglyceride
levels than compactin or lovastatin. Moreover, fluvastatin exhibits a unique set of
pharmacological properties including a biopharmaceutical profile most consistent
with hepatoselectivity. It has been reported to be well tolerated and to exhibit a
safety profile superior to other agents of its class. The main mechanism by which
HMG-CoA reductase inhibitors lower plasma cholesterol has been suggested to be
up-regulation of hepatocellular LDL-receptor expression and enhancement of
receptor-mediated clearance and catabolism of LDL cholesterol.
Chemische Eigenschaften
Yellow Powder
Verwenden
Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
Allgemeine Beschreibung
Fluvastatin sodium is a lipid-lowering drug that belongs to the group of compounds known as statins. It acts by inhibiting the enzyme HMG-CoA reductase that plays a key role in the cholesterol production. It is generally used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biologische Aktivität
Orally active, potent and competitive HMG-CoA reductase inhibitor (IC 50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC 50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo .
Fluvastatin sodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fluvastatin sodium salt Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 367)Lieferanten
93957-55-2()Verwandte Suche:
- sodium (3r,5s,6e)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl]-3,5-dihydroxy-6-heptenoate
- (+/-)-(3R',5S',6E)-7-[3-(4-FLUOROPHENYL)-1-ISOPROPYLINDOL-2-YL]-3,5-DIHYDROXY-6-HEPTENOATE, SODIUM
- FLUVASTATIN NA
- FLUVASTATIN SODIUM SALT
- (r*,s*-(e))-monosodiumsal(+-)-2-yl)
- 3,5-dihydro-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-6-heptenoicaci
- 5-dihydro-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl)-monosodiumsalt,(r*,s*-(e))-(6-heptenoicaci
- (E)-SODIUM 3,5-DIHYDROXY-7-[3- (4-FLUOROPHENYL)-1-(1-METHYLETHYL 1H-INDOL-2-YL)HEPT-6-ENOATE
- Fluvastatin (Lescol)
- Fluvastatin SodiuM Salt Hydrate
- Fluvastatin SodiuM API
- Fluvastatin SodiuM Salt
(Relative StereocheMistry)
- sodiuM (3S,5R,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate
- Fluvastatin sodium salt sodium(3r,5s,6e)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl]-3,5-dihydroxy- 6-heptenoate
- (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt hydrate
- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
- InSolution? Fluvastatin, Sodium Salt
- fluindostatin
- xu62-320
- Sodium( +-) (E)-3,5-dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethyl- indol-2'-yl] hept-6-enoate
- (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacidsodiumsalt
- Fluvastatin sodium s
- Fluvastatin Sodium (350 mg)
- (3S,5R)-7-(3-(4-FLUOROPHENYL)-1-ISOPROPYL-1H-INDOL-2-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID SODIUM SALT
- (3S,5R)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-
- sodium (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-yl-indol-2-yl]-3,5-dihydroxy-hept-6-enoate
- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
- [R^<*>^，S^<*>^ -(E)](±)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-y1]-3，5-dihydroxy-6-heptenoic acid sodium salt
- 7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium
- (E)-3,5-dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethyl-indol-2'-yl] hept-6-enoate
- Fluvastatin Sodium n -Hydrate
- Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem
- InSolution Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem
- sodium 7-[3-(4-fluorophenyl)-1-propan-2-yl-2-indolyl]-3,5-dihydroxy-6-heptenoate
- Fluvastatin sodium CRS
- [2H6]- Fluvastatin Sodium Salt
- Fluvastatin for system suitability CRS
- FluvastatinSodiumSaltHydrate>
- XU 62320 sodium
- rel-(3S,5R,E)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid, sodium salt
- sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
- Fluvastatin sodium salt USP/EP/BP
- Fluvastatin Sodium SaltQ: What is
Fluvastatin Sodium Salt Q: What is the CAS Number of
Fluvastatin Sodium Salt Q: What is the storage condition of
Fluvastatin Sodium Salt Q: What are the applications of
Fluvastatin Sodium Salt
- Fluvastatin D6 sodiumQ: What is
Fluvastatin D6 sodium Q: What is the CAS Number of
Fluvastatin D6 sodium Q: What is the storage condition of
Fluvastatin D6 sodium Q: What are the applications of
Fluvastatin D6 sodium
- Fluvastatin Sodium (1285931)
- (+)-Pinanediol
- 3-cis/exo-pinanediol
- 3-cs/ex-PinD
- FLUVASTATIN SODIUM
- Fluvastatin sodium hydrate
- Flurastatin Sodium
- FLUVASTATIN
- Fluvastatin Sodium Salt Hydrate, ≥ 98.0%
- Fluvastatin (XU-62-320) Sodium
- 93957-55-2
- C24H25FNNaO4
- C24H26FNO4Na
- C24H25FNNaO4xH2O
