2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
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- CAS-Nr.
- 6564-72-3
- Englisch Name:
- 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
- Synonyma:
- Voglibose int;benzylglucopyranose;Tetrabenzyl glucose;Voglibose Impurity 1;Voglibose TBG IMpurity;Voglibose TBG impurities;Voglibose alpha-TBG Impurity;2,3,4,6-tetra-o-benzyl-d-glucose;6-Tetra-O-benzyl-D-glucopyranose;2,3,4,6-Tetra-o-benzyl-D-glucopyransoe
- CBNumber:
- CB0234449
- Summenformel:
- C34H36O6
- Molgewicht:
- 540.66
- MOL-Datei:
- 6564-72-3.mol
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2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Eigenschaften
- Schmelzpunkt:
- 151-156 °C
- Siedepunkt:
- 672.4±55.0 °C(Predicted)
- Dichte
- 1.22
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- 11.87±0.70(Predicted)
- Wasserlöslichkeit
- Soluble in CHCl3. Insoluble in water.
- LogP
- 5.9 at 20℃ and pH6.5
- CAS Datenbank
- 6564-72-3(CAS DataBase Reference)
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU.
Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form.
Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.
Verwenden
It is the intermediate of Voglibose/Dapagliflozin. An important D-glucopyranose derivative for glucosylations and other reactions 1,2; Preparation of the α-glucopyranosyl chloride, synthesis of 1-C-α-D-glucopyranose derivatives.
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 290)Lieferanten
6564-72-3()Verwandte Suche:
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose (for Voglibose)
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSIDE
- 2,3,4,6-TETRA-O-BENZOYL-D-GLUCOPYRANOSE
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose
- benzylglucopyranose
- 6-Tetra-O-benzyl-D-glucopyranose
- 2,3,4,6-tetra-o-benzyl-d-glucose
- 2,3,4,6-Tetra-o-benzyl-D-glucopyransoe
- 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranose
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE ,GB
- 2,3,4,6-TETRA-O-ACETYL A-D-GLUCOPYRANOSIDE
- 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranos
- alpha-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylMethyl)-
- a-D-Glucopyranose,2,3,4,6-tetrakis-O-(phenylMethyl)-
- Voglibose TBG IMpurity
- (2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)Methyl)tetrahydro-2H-pyran-2-ol
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose SynonyMs 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose
2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose
- Voglibose int
- Voglibose Impurity 1
- 2,3,4,6-Tetra-O-benzyl-D-glycopyranose
- Voglibose TBG impurities
- Voglibose alpha-TBG Impurity
- 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose
- 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOSE 6564-72-3
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE USP/EP/BP
- 2,3,4,6-TETRA-O-BENZYL-ALPHA GLUCOPYRANOSE（COM）
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCChemicalbookOPYRANOSE
- 2,3,4,6-Tetra-O-benzyl-D-glucopyranose(TBG)
- 2,3,4,6-Tetrakis-O-(phenylmethyl)-α-D-glucopyranose
- α-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylmethyl)-
- Tetrabenzyl glucose
- 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
- 6564-72-3
- Specialty Synthesis
- Monosaccharides
- Monosaccharide
- O-Substituted Sugars
- Sugars
- Carbohydrate Synthesis
- Carbohydrates
- Biochemicals and Reagents
- BioChemical
- Pharmaceutical Intermediates
- 6564-72-3
