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4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE

4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Struktur
606-58-6
CAS-Nr.
606-58-6
Englisch Name:
4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
Synonyma:
e-212;e-212-1;a-399-y4;NSC 99843;NSC 63701;siromycin;uramycinb;vengicide;unamycin-b;fungamycin
CBNumber:
CB0235800
Summenformel:
C12H13N5O4
Molgewicht:
291.26
MOL-Datei:
606-58-6.mol
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4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Eigenschaften

Schmelzpunkt:
243°; mp 239-243°
alpha 
D16 -45.7° (c = 1.05 in 0.1N HCl)
Siedepunkt:
433.28°C (rough estimate)
Dichte
1.3067 (rough estimate)
Brechungsindex
1.7000 (estimate)
storage temp. 
2-8°C
Löslichkeit
DMSO: soluble0.90 - 1.10mg/mL, clear, colorless
Aggregatzustand
solid
pka
12.31±0.70(Predicted)
Farbe
White or off-white
Stabilität:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Toxizität LD100 s.c. in mice: 10-20 mg/kg (Nishimura)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Toyocamycin is a pyrrolopyrimidine nucleoside isolated from Streptomyces toyocaensis in 1956. Toyocamycin, like other members of pyrrolopyrimidine class, is an adenosine nucleotide antimetabolite, with a broad spectrum of action against bacteria, fungi, protozoans and mammalian cell lines.

Biochem/physiol Actions

Studies have implicated that toyocamycin blocks the replication of fowl plague virus.

4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Jaspamycin

4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 68)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Beijing Ribio Biotech Co.,Ltd 		010-62664360 +8613328773880
 wucy@ribio.com.cn China 117 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629
 sales@newcanbio.com China 10026 58
Alfa Chemistry 		+1-5166625404
Info@alfa-chemistry.com United States 21317 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49739 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3136 58
ZHEJIANG JIUZHOU CHEM CO., LTD 		+86-0576225566889 +86-13454675544
 admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com China 20000 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 		+86-19164747840 +86-13119157289
 13119157289@163.com China 2971 58

606-58-6()Verwandte Suche:

7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin
  • NSC 63701
  • NSC 99843
  • TOYOCAMYCIN
  • 3-d)pyrimidine-5-carbonitrile,4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(
  • 4-amino-5-cyano-7-(d-ribofuranosyl)-7h-pyrrolo(2,3-d)pyrimidine
  • 4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine-5-carbonitrile
  • a-399-y4
  • ahygroscopin-b
  • antibiotic1037
  • antibiotica-399-y4
  • antibiotice212
  • cyanotubericidin
  • e-212
  • e-212-1
  • naritheracin
  • siromycin
  • toyocamycinnucleoside
  • unamycin-b
  • uramycinb
  • vengicide
  • 7-CYANO-7-DEZXAADENOSINE
  • 4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
  • 4-AMINO-7-SS-D-RIBOFURANOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE
  • Cyanotubercidin, UnaMycin B, Vengicide, E 212, 1037, E 212, Anhygroscopin B, Naritheracin
  • 4-Aminopyrrolo[2,3-d]pyrimidine-5-carbonitrile 7-(β-D-ribofuranoside)
  • 7-Deaza-7-cyanoadenosine
  • Neuro 000027
  • 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
  • 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 4-amino-7-β-D-ribofuranosyl-
  • TOYOCAMYCIN (VENGICIDE)
  • 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
  • 4-Amino-5-cyano-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
  • Toyacamycin
  • RNA synthesis,CDK,mRNA cleavage,epigenetics,Toyocamycin,IRE1,CDK9 inhibitor,Cyclin dependent kinase,molecular docking,reactive oxygen species,CDKs,RNA Pol II phosphorylation,Inositol requiring enzyme 1,Fungal,Inhibitor,adenosine analog,Antibiotic,drug screening,ribosome function,inhibit,Apoptosis,extracellular signal-regulated kinases,cancer
  • 7H-Pyrrolo[2,3-D]pyrimidine-5-carbonitrile,4-amino-7-b-d-ribofuranosyl-
  • fungamycin
  • 7-Cyano-7-deoxyadenosine
  • 606-58-6
  • C12H13N5O4
  • C12H13N5O4H2O
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