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COMPOUND 401

COMPOUND 401 Struktur
168425-64-7
CAS-Nr.
168425-64-7
Englisch Name:
COMPOUND 401
Synonyma:
CS-315;Morpholino a;Compound 401, >=98%;COMPOUND401;COMPOUND-401;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
CBNumber:
CB02458229
Summenformel:
C16H15N3O2
Molgewicht:
281.31
MOL-Datei:
168425-64-7.mol
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COMPOUND 401 Eigenschaften

Schmelzpunkt:
184-186℃ (ethanol )
Siedepunkt:
456.9±55.0 °C(Predicted)
Dichte
1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Store at RT
Löslichkeit
DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
pka
1.01±0.20(Predicted)
Aggregatzustand
powder to crystal
Farbe
White to Light yellow
CAS Datenbank
168425-64-7

Sicherheit

HS Code  2934.99.4400

COMPOUND 401 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Compound 401 is a selective inhibitor of DNA-PK and FRAP.

Biologische Aktivität

Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC 50 values are 0.28 and 5.3 μ M respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC 50 values are all > 100 μ M). Induces apoptosis in vitro .

COMPOUND 401 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

COMPOUND 401 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 74)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
  • 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
  • 4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-
  • 2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one
  • 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
  • Compound 401, >=98%
  • 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
  • CS-315
  • COMPOUND401;COMPOUND-401
  • 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>
  • Morpholino a
  • DNA-PK,Compound401,DNA-dependent protein kinase,Compound-401,Compound 401,inhibit,Inhibitor
  • 168425-64-7
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