Oxalessigsure
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- CAS-Nr.
- 328-42-7
- Bezeichnung:
- Oxalessigsure
- Englisch Name:
- Oxobutanedioic acid
- Synonyma:
- OXALOACETIC ACID;OXALACETIC ACID;2-OXOSUCCINIC ACID;OAA;oxalacetic;NSC 77688;NSC 284205;2-OXOSUCCINIC;OXLACETIC ACID;oxaloaceticaci
- CBNumber:
- CB0271682
- Summenformel:
- C4H4O5
- Molgewicht:
- 132.07
- MOL-Datei:
- 328-42-7.mol
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Oxalessigsure Eigenschaften
- Schmelzpunkt:
- 161 °C (dec.)(lit.)
- Siedepunkt:
- 163.94°C (rough estimate)
- Dichte
- 1.3067 (rough estimate)
- Dampfdruck
- 0.003Pa at 20℃
- Brechungsindex
- 1.4000 (estimate)
- Flammpunkt:
- 88°C
- storage temp.
- -20°C
- Löslichkeit
- H2O: 100 mg/mL
- Aggregatzustand
- powder
- pka
- 2.22(at 25℃)
- Farbe
- White to off-white
- PH
- 3.05(1 mM solution);2.29(10 mM solution);1.68(100 mM solution)
- Wasserlöslichkeit
- soluble
- Merck
- 14,6909
- BRN
- 1705475
- Stabilität:
- Stable. Incompatible with strong oxidizing agents. Keep refrigerated.
- LogP
- -1.04 at 20℃
- CAS Datenbank
- 328-42-7(CAS DataBase Reference)
- NIST chemische Informationen
- Oxalacetic acid(328-42-7)
- EPA chemische Informationen
- Oxalacetic acetic (328-42-7)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
C |
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| R-Sätze: |
34 |
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| S-Sätze: |
26-36/37/39-45 |
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| RIDADR |
UN 3261 8/PG 2 |
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| WGK Germany |
3 |
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| TSCA |
Yes |
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| HazardClass |
8 |
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| PackingGroup |
II |
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| HS Code |
29183000 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P337+P313 |
Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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Oxalessigsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Oxaloacetic acid is an α-keto acid and a key component of cellular metabolism in its conjugate base form, oxaloacetate. Oxaloacetate reacts with acetyl-coenzyme A (acetyl-CoA; ) and water to form citrate in the first step of the citric acid cycle and is regenerated by oxidation of L-malate in the final step. It is an intermediate in gluconeogenesis that is formed in mitochondria
via carboxylation of pyruvate and subsequently decarboxylated and phosphorylated to form phosphoenolpyruvate. It can be converted to aspartate
via addition of an amino group from glutamate. Oxaloacetate (30 μmol/min per 100 g for 30 minutes, i.v.) reduces blood glutamate levels, severity of neurological dysfunction, and brain edema in a rat model of closed head injury.
Chemische Eigenschaften
off-white crystals
Verwenden
A four carbon dicarboxylic acid that is an intermediate in the citric acid cycle and glucogenesis. It has been shown to inhibit succinate dehydrogenase.
Definition
ChEBI: An oxodicarboxylic acid that is succinic acid bearing a single oxo group.
Allgemeine Beschreibung
Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid.
läuterung methode
Crystallise it from boiling EtOAc, or from hot Me2CO/hot *C6H6. [Beilstein 3 IV 1808.]
Oxalessigsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Oxalessigsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 280)Lieferanten
328-42-7(Oxalessigsure)Verwandte Suche:
- OXOBUTANEDIOIC ACID
- OXOBUTANEDIOTIC ACID
- OXOSUCCINIC ACID
- OXLACETIC ACID
- OXALEACETIC ACID
- oxalacetic acid hybri-maxtm
- oxo-butanedioicaci
- Oxalacetic acid 2-Oxosuccinic
- OXALACETIC ACID, CELL CULTURE TESTED
- OXALACETIC ACID HYBRI-MAX
- OxalaceticAcid,~98%
- Ketosuccinic acid, Oxosuccinic acid
- 2-Oxosuccinic acid, Ketosuccinic acid, Oxalacetic acid, Oxobutanedioic acid
- 2-Ketosuccinic acid
- Butanedioic acid, oxo-
- 2-Oxosuccinic acid, Ketosuccinic acid, Oxalacetic acid, Oxaloacetic acid, Oxobutanedioic acid
- 2-Oxosuccinic acid, Oxobutanedioic acid
- KETOSUCCINIC ACID
- Oxalacetic acid,96%
- 2-OXOSUCCINIC
- NSC 284205
- NSC 77688
- Oxaloethanoic Acid
- Oxalacetic acid, 98% 5GR
- Butanedioic acid,2-oxo-
- Oxalacetic acid SynonyMs 2-Oxosuccinic acid
- Oxalacetic acid,cis form
- OXALOACETIC ACID, >=97% (HPLC)
- Oxaloacetic Acid - CAS 328-42-7 - Calbiochem
- OxalaceticAcid>
- Malic Acid Impurity 5
- oxaloaceticaci
- Oxalacetic Acid for cell culture, 98%
- PRT062607 (P505-15
- OXALACETIC ACID
- OXALOACETIC ACID
- OAA
- 2-OXOSUCCINIC ACID
- oxalacetic
- 328-42-7
- HOOCCOCH2COOH
- C4H4O5
- HOOCCH2COCOOH
- HO2CCH2COCO2H
- C1 to C5
- Carboxylic Acids
- Carbonyl Compounds
- BioChemical
- Biochemicals and Reagents
- Building Blocks
- Enzymes, Inhibitors, and Substrates
- Enzyme Substrates
- Substrates by Enzyme
- Oxaloacetate decarboxylase
- Organic Building Blocks
- Metabolomics
- Metabolites and Cofactors on the Metabolic Pathways Chart
- Metabolic Pathways
