9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on
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- CAS-Nr.
- 7385-67-3
- Bezeichnung:
- 9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on
- Englisch Name:
- Nile Red
- Synonyma:
- NILE BLUE A OXAZONE;Fluorescent Spectral Standard E, certified;9-(DIETHYLAMINO)-5H-BENZO[A]PHENOXAZIN-5-ONE;nile;NILE RED;nilereddye;Phenoxazone;Oxazine O-17M;Nile Red ,99%;Phenoxazone 9
- CBNumber:
- CB0273873
- Summenformel:
- C20H18N2O2
- Molgewicht:
- 318.37
- MOL-Datei:
- 7385-67-3.mol
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9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on Eigenschaften
- Schmelzpunkt:
- 203-205 °C(lit.)
- Siedepunkt:
- 457.53°C (rough estimate)
- Dichte
- 1.1871 (rough estimate)
- Brechungsindex
- 1.5700 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- methanol: soluble1mg/mL
- Aggregatzustand
- Powder
- pka
- 4.08±0.20(Predicted)
- Farbe
- Dark red to maroon
- BRN
- 279110
- Stabilität:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
- InChIKey
- VOFUROIFQGPCGE-UHFFFAOYSA-N
- SMILES
- C12=CC=CC=C1C(=O)C=C1C2=NC2=C(C=C(N(CC)CC)C=C2)O1
- CAS Datenbank
- 7385-67-3(CAS DataBase Reference)
- EPA chemische Informationen
- 5H-Benzo[a]phenoxazin-5-one, 9-(diethylamino)- (7385-67-3)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
24/25 |
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| WGK Germany |
3 |
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| F |
8-10 |
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| HS Code |
29349990 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Nile red is a dye based on the benzo[a]phenoxazine core. Nile Red (9-diethylbenzo[a]phenoxazin-5- one) stands out as electrically neutral and water-insoluble since it features a carbonyl group at the 5-position that readily accepts the electron density. This makes it a strong push?pull chromophore, which underlies its distinct solvatochromicity and ability to indicate, e.g., cellular events in live-cell imaging. In addition, Nile Red’s inherent lipophilicity, near-infrared (NIR) emission, large Stokes shift, two-photon absorptivity (2PA), and low background fluorescence (as the luminosity is quenched in aqueous (aq) media) render it a near-ideal histochemical stain for studying membranes and lipid droplets in cells. The increase of its exquisite solvent sensitivity and steep emission in hydrophobic environments has also been employed in various forms of stochastic super-resolution localization microscopy[1].
Chemische Eigenschaften
solid
Verwenden
Nile red is a lipophilic stain. Nile red stains intracellular lipid droplets. Nile red is also intensely fluorescent, with a strong yellow-gold emission if included into a lipid-rich environment.
Definition
ChEBI: An organic heterotetracyclic compound that is 5H-benzo[a]phenoxazin-5-one substituted at position 9 by a diethylamino group.
Allgemeine Beschreibung
Nile Red is an uncharged hydrophobic molecule and a benzophenoxazone dye. It functions as a fluorescent probe for intracellular lipids and hydrophobic domains of proteins. This dye is fluorescent in all organic solvents. Its fluorescence colors range from golden yellow to deep red.
9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 245)Lieferanten
7385-67-3(9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on)Verwandte Suche:
- NILE RED
- 9-(diethylamino)-5h-benzo[a]phenoxazin-5-on
- nile
- 9-(diethylamino)benzo[a]phenoxazin-5(5H)-one
- FLUORESCENCE QY-STANDARD E CERTIFIED
- 9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on
- Nile Red, pure, 99%
- 9-Diethylamino-benzo[a]phenoxazin-5-one
- 7-(Diethylamino)-1,2-[1,3]butadieno-3H-phenoxazine-3-one
- 9-Diethylamino-5H-benzo[a]phenoxazine-5-one
- Oxazine O-17M
- Phenoxazone
- Nile Red,99%,pure
- Nile Red ,99%
- Nile Red,Nile Blue A Oxazone
- 9-Diethylaminobenzo[a]phenoxazone
- Nile Red, pure, 99% 100MG
- Phenoxazone 9
- 5H-Benzo[a]phenoxazin-5-one,9-(diethylaMino)-
- Nile red, Determination of lipids, staining whole tissue
- Nile Red, Fluorescent stain for intracellular lipid droplets.
- NILE RED SUITABLE FOR FLUORESCENCE
- Nile Red *CAS#: 7385-67-3*
- Nile Red, 97.5%
- nilereddye
- Nile red, for microscopy
- Nile red, ≥98%
- Nile red, puriss
- NILE BLUE A OXAZONE
- 9-(DIETHYLAMINO)-5H-BENZO[A]PHENOXAZIN-5-ONE
- Fluorescent Spectral Standard E, certified
- 7385-67-3
- C20H18N2O2
- Electroluminescence
- BioChemical
- Biochemicals and Reagents
- Other Fluorescent Labels
- Lipophilic and Membrane Probes
- Fluorescent Probes, Labels, Particles and Stains
- Fluorescence Standards
- Fluorescent Indicators and Probes
- Fluorescent Labels
- Alphabetical
- marker
- Electroluminescence
- Functional Materials
