1,1'-Thiocarbonylbis(imidazol)
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- CAS-Nr.
- 6160-65-2
- Bezeichnung:
- 1,1'-Thiocarbonylbis(imidazol)
- Englisch Name:
- 1,1'-Thiocarbonyldiimidazole
- Synonyma:
- TCDI;Di(1H-imidazol-1-yl)methanethione;1,1-THIOCARBONYLDIIMIDAZOLE;Thiocarbonyl diimidazole;bis(1H-imidazol-2-yl)methanethione;DiiMidaz;diimidazoL;1,1'-THIOCARBONYL;1,1'-Thiocarbonyldii;Thiocarbonylbisimidazole
- CBNumber:
- CB0280138
- Summenformel:
- C7H6N4S
- Molgewicht:
- 178.21
- MOL-Datei:
- 6160-65-2.mol
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1,1'-Thiocarbonylbis(imidazol) Eigenschaften
- Schmelzpunkt:
- 98-102 °C(lit.)
- Siedepunkt:
- 342°C (rough estimate)
- Dichte
- 1.3046 (rough estimate)
- Brechungsindex
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- Soluble in terahydrofuran, toluene and dichloromethane.
- pka
- 1.96±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- Bright yellow
- Wasserlöslichkeit
- decomposes
- Sensitive
- Moisture Sensitive
- BRN
- 609349
- Stabilität:
- Stable, but air and moisture sensitive. Incompatible with strong oxidizing agents, strong acids.
- InChIKey
- RAFNCPHFRHZCPS-UHFFFAOYSA-N
- CAS Datenbank
- 6160-65-2(CAS DataBase Reference)
1,1'-Thiocarbonylbis(imidazol) Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
yellow powder
Application
1,1′-Thiocarbonyldiimidazole (TCDI) is generally used as a reagent to carry out the deoxygenation of vicinal diols by forming cyclic thionocarbonate in Corey-Winter alkene synthesis.
It is used as a reagent in the enantioselective total synthesis of (+)-hapalindole Q, 12-epi-fischerindole U and welwitindolinone A.
It is also used in the preparation of trithiocarbonates, xanthates, and dithiocarbamates as chain transfer agents for the reversible addition fragmentation chain transfer and macromolecular design (RAFT/ MADIX) polymerization.
Verwenden
1,1'-Thiocarbonyldiimidazole is used as a reagent for the deoxygenation of alcohols with tributyltin hydride and diols with lithium aluminum hydride. It is also used to deoxygenate carboxylic monosaccharide analogues. Further, it is a useful reagent involved in biochemical synthesis. In addition to this, it is used to prepare 1-[bis-(4-methoxy-phenyl)-methyl]-1H-imidazole by reacting with 4,4'-dimethoxy-benzhydrol.
läuterung methode
It forms yellow crystals on recrystallisation from tetrahydrofuran or by sublimation at 10-3torr (bath temperature 70-80o). It is hydrolysed by H2O and should be stored dry. [Staab & Walther Justus Liebigs Ann Chem 657 98 1962; Pullukat et al. Tetrahedron Lett 1953 1967, Hanessian et al. Can J Chem 65 1859 1987, Rajanbabu et al. J Am Chem Soc 111 1759 1989.] Thiochrome {2,7-dimethyl-5H -thiachromine-8-ethanol; 3,8-dimethyl-2-hydroxyethyl-5H -
1,1'-Thiocarbonylbis(imidazol) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-Methyl-2-imidazolidinethione
3-Phenylpropylisothiocyanat
(S)-4-PHENYL-1,3-OXAZOLIDINE-2-THIONE
bis(benzylsulfanyl)methanethione
4-Isothiocyanatobenzene-1-sulfonamide
4,4-DIMETHYL-2-OXAZOLIDINONE
1,3-Di-o-tolyl-2-thioharnstoff
3-CHLOROPHENYL ISOTHIOCYANATE
4-(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE
NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-
3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
1,2,4-Triazolo[4,3-b]pyridazine-6-carboxylic acid, 2,3-dihydro-3-thioxo-, methyl ester
N-(1H-INDAZOL-6-YL)THIOUREA
1H-Imidazole-1-carbothioic acid, O-propyl ester
Benzene, 1-fluoro-4-(2-isothiocyanatoethyl)-
Dimorpholino thioketone
1,1'-Thiocarbonylbis(imidazol) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 470)Lieferanten
6160-65-2(1,1'-Thiocarbonylbis(imidazol))Verwandte Suche:
1,1'-Carbonylbis-1H-imidazol
Imidazol
Fenbendazol
Albendazole
Trimethylsilyl-N-trimethylsilyl-acetamidat
N,N,-Dibenzylethylendiammoniumdi-(acetat)
N,N'-Methantetraylbis(1-methylethylamin)
N,N-Dimethyl-p-toluidin
Di(succinimido)carbonat
1,1,2-Trichlor-2,3,3-trifluorcyclobutan
Thiamazol
1-Methylimidazol
1,1'-Thiocarbonylbis(imidazol)
- N,N'-THIOCARBONYLDIIMIDAZOLE
- 1,1'-thiocarbonylbis(imidazole)
- 1,1'-THIOCARBONYLDIIMIDAZOLE
- 1-(1H-IMidazol-1-ylcarbothioyl)-1H-iMidazole
- DiiMidaz
- 1,1'-CARBONOTHIOYLBIS-1H-IMIDAZOLE
- N, N - sulfur carbonyl iMidazole
- 1,1'-Thiocarbonyldiimidazole >=95.0% (S)
- 1,1'-Thiocarbonyldiimidazole technical grade, 90%
- 1,1'-Thiocarbonyldiimidazole, technical, 90%
- 1,1'-THIOCARBONYLDIIMIDAZOLE, TECH., 90%
- N,N'-THIOCARBONYLDIIMIDAZOLE(TCDI)
- 1,1,-ThiocarbonyldiimidazoleTech90%
- 1,1'-Thiocarbonyldiimidazole,95%
- 1H-Imidazole, 1,1-carbonothioylbis-
- N,N’-Thiocarboryldiimidazole
- 1,1''-THIOCARBONYLDIIMIDAZOLE (TCDI)
- Bis(1H-imidazole-1-yl) thioketone
- Bis(1-imidazolyl) thioketone
- Di(imidazol-1-yl)methanethione
- Thiocarbonylbisimidazole
- 1,1'-Thiocarbonyldiimidazole,90%,tech.
- 1.1'-Thiocarbonyldiimidazole 100mg [6160-65-2]
- 1,1'-Thiocarbonyldiimidazole, tech 90%
- 1,1'-Thiocarbonyldii
- N'-ThiocarbonyldiiMidazole(TCDI)
- 1,1'-Thiocarbonyldi(1H-imidazole) 90%
- 1,1'-THIOCARBONYL
- diimidazoL
- 1,1'-Thiocarbonyldiimidazole >
- Methanethione, di-1H-imidazol-1-yl-
- 1,1'-Thicarbonyldiimidazole
- TIANFU-CHEM 6160-65-2 1,1'-Thiocarbonyldiimidazole
- TCDI
- 1,1-THIOCARBONYLDIIMIDAZOLE
- Thiocarbonyl diimidazole
- Di(1H-imidazol-1-yl)methanethione
- bis(1H-imidazol-2-yl)methanethione
- THEOCARBONYL DIIMIDAZOLE
- 1,1'-Thiocarbonyldiimidazole
- 6160-65-2
- 228-183-4
- Building Blocks
- Carbonyldiimidazole Derivatives
- Synthetic Reagents
- Imidazoles
- Coupling
- Heterocyclic Building Blocks
- Carbonyldiimidazole Derivatives
- Coupling
- Synthetic Reagents
- Carbonyldiimidazole DerivativesBuilding Blocks
- Heterocyclic Building Blocks
- Imidazoles
