Proteasome Inhibitor XVI

Proteasome Inhibitor XVI Struktur
389064-25-9
CAS-Nr.
389064-25-9
Englisch Name:
Proteasome Inhibitor XVI
Synonyma:
Proteasome Inhibitor XVI;AdaAhxLVS - CAS 389064-25-9 - Calbiochem;L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]-
CBNumber:
CB03121496
Summenformel:
C50H88N6O8S
Molgewicht:
933.33
MOL-Datei:
389064-25-9.mol

Proteasome Inhibitor XVI Eigenschaften

Siedepunkt:
1161.4±65.0 °C(Predicted)
Dichte
1.096±0.06 g/cm3(Predicted)
storage temp. 
-20C
Aggregatzustand
Off-white powder
pka
13.41±0.46(Predicted)

Sicherheit

Proteasome Inhibitor XVI Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM).

Biochem/physiol Actions

Cell permeable: yes

Proteasome Inhibitor XVI Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Proteasome Inhibitor XVI Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412
sales@alphabiopharm.com China 886 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518
sales@alabiochem.com China 995 59
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Alabiotech Inc. 001-619-354-5251
sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497
sales@alphabiopharm.com China 1951 58

  • Proteasome Inhibitor XVI
  • AdaAhxLVS - CAS 389064-25-9 - Calbiochem
  • L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]-
  • 389064-25-9
  • C50H88N6O8S
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