Dinatriumdihydrogen(dichloromethylen)diphosphonat
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- CAS-Nr.
- 22560-50-5
- Bezeichnung:
- Dinatriumdihydrogen(dichloromethylen)diphosphonat
- Englisch Name:
- Clodronate disodium
- Synonyma:
- DMDP;Loron;CL2MDP;bm06011;U-82067E;lodronate;Difosfonal;clodronatesodium;sodiumclodronate;chlodronatesodium
- CBNumber:
- CB0318011
- Summenformel:
- CH5Cl2NaO6P2
- Molgewicht:
- 268.88
- MOL-Datei:
- 22560-50-5.mol
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Dinatriumdihydrogen(dichloromethylen)diphosphonat Eigenschaften
- Schmelzpunkt:
- >330°C
- storage temp.
- room temp
- Löslichkeit
- Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChIKey
- HJKBJIYDJLVSAO-UHFFFAOYSA-L
- CAS Datenbank
- 22560-50-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| RTECS-Nr. |
SZ7640700 |
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| HS Code |
29319090 |
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| Toxizität |
mouse,LD50,intraperitoneal,780mg/kg (780mg/kg),British UK Patent Application. Vol. #2096889, |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Dinatriumdihydrogen(dichloromethylen)diphosphonat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Clodronate disodium is a bone resorption inhibitor, useful as adjunct therapy in the treatment of osteolytic bone metastases and malignant hypercalcemia.
Chemische Eigenschaften
White Solid
Definition
ChEBI: The disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteoly
ic lesions and bone pain associated with skeletal metastases.
Hazard
Moderately toxic by ingestion.
Sicherheitsprofil
A poison by intravenous route. Moderately toxic by ingestion, intraperitoneal routes. When heated to decomposition it emits toxic vapors of PO, and Cl-
Dinatriumdihydrogen(dichloromethylen)diphosphonat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dinatriumdihydrogen(dichloromethylen)diphosphonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 152)Lieferanten
22560-50-5(Dinatriumdihydrogen(dichloromethylen)diphosphonat)Verwandte Suche:
- CL2MDP
- Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2)
- Clodronate disodium, >=98%
- DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT
- DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT
- DMDP
- CLODRONIC ACID DISODIUM SALT
- CLODRONATE DISODIUM
- (dichloromethylene)bis-phosphonicacidisodiumsalt
- (dichloromethylene)di-phosphonicacidisodiumsalt
- bm06011
- chlodronatesodium
- clodronatesodium
- dichloromethanediphosphonate
- disodium(dichloromethylene)bisphosphonate
- disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxy-phosphinate
- Clodronic Acid, Disodium Salt, Hydrate
- disodiumclodronate
- lodronate
- sodiumclodronate
- Clodronate Disodium, Bonefos, Clasteon, Clastoban
- disodium dihydrogen (dichloromethylene)diphosphonate
- DICHLOROMETHYLENEDIPHOSPHONIC ACID
- ClodronateAcidDisodiumSalt
- clodronate disodium，CLD
- Difosfonal
- Loron
- (Dichloromethylene)bis(phosphonic acid hydrogen sodium) salt
- Disodium crodronate
- U-82067E
- disodium [dichloro-[hydroxy(oxidanidyl)phosphoryl]methyl]-hydroxy-phosphinate
- disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate
- clodronic acid, sodium salt
- Cl2MDP, Clodronic acid disodium salt, DMDP
- (Dichloromethylene)diphosphonate disodium
- disodium [dichloro(phosphonato)methyl]-dioxido-oxophosphorane
- clodronicaciddisodiumsal
- CAS22560-50-5 clodronic acid disodium salt
- Sodium (dichloro(phosphono)methyl)phosphonate
- 22560-50-5
- CH2Cl2O6P22Na
- CH2Cl2Na2O6P2
- CH2O6Cl2Na2P2
- CH4Cl2O6P02Na
- Clodronic Acid Disodium
- Other APIs
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Phosphorylating and Phosphitylating Agents
- All Inhibitors
- 22560-50-5
