1,2,3,4-Diepoxybutan Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R46:Kann vererbbare Schäden verursachen.
R24/25:Giftig bei Berührung mit der Haut und beim Verschlucken.
R26:Sehr giftig beim Einatmen.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
clear colorless to very slightly yellow liquid
Verwenden
Diepoxybutane has been used as a research chemical, as a chemical intermediate, as a curing agent for polymers, as a cross-linking agent for textile fabrics, and to prevent microbial spoilage (IARC 1976, HSDB 2009). It has also been used to synthesize erythritol and pharmaceuticals (HSDB 2009). Because of its cross-linking properties, diepoxybutane is used as a test agent in the diagnosis of Fanconi anemia, which is characterized by chromosomal instability (Auerbach et al. 1989).
Vorbereitung Methode
Diepoxybutane is prepared by chlorination of butadiene
followed by epoxidation with peracetic acid, with subsequent
hydrolysis of the epoxide group and final reepoxidation with
caustic.
Allgemeine Beschreibung
Colorless liquid. Used in curing polymers; crosslinking textile fibers and to prevent spoilage.
Air & Water Reaktionen
Highly Flammable
Reaktivität anzeigen
Epoxides, such as 1,3-BUTADIENE DIEPOXIDE, are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
Hazard
Probable carcinogen; neoplastigen; tumorigenic; poison; mutagen.
Health Hazard
Severe skin and eye irritant. Accidental minor exposure caused swelling of the eyelids, upper respiratory tract irritation and painful eye irritation 6 hours after exposure.NOTE: The dl- and meso-forms (CAS Registry Numbers 298-18-0 and 564-00-1, respectively) as well as the L(-) form (CAS Registry Number 30031-64-2) have all been determined to be positive animal carcinogens.
Brandgefahr
When heated to decomposition 1,3-BUTADIENE DIEPOXIDE emits acrid smoke and irritating fumes.
Sicherheitsprofil
Confirmed carcinogen withexperimental tumorigenic data. Poison by ingestion,inhalation, skin contact, and intraperitoneal routes.Human mutation data reported. A severe skin and eyeirritant. When heated to decomposition it emits acridsmoke and irritat
Carcinogenicity
Diepoxybutane is reasonably anticipated to be a human carcinogenbased on sufficient evidence of carcinogenicity from studies in experimental animals.
1,2,3,4-Diepoxybutan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
