ChemicalBook
Chinese english Germany Japanese Korea

1,2,3,4-Tetrahydronaphthalin-2-on Produkt Beschreibung

beta-Tetralone Struktur
530-93-8
CAS-Nr.
530-93-8
Bezeichnung:
1,2,3,4-Tetrahydronaphthalin-2-on
Englisch Name:
beta-Tetralone
Synonyma:
Tetralon;β-TetraL;NSC 87083;TETRALONE-2;2-TETRALONE;B-TETRALONE;β-Tetralone;2-Oxotetralin;β-4-tetralone;Tetralin-2-one
CBNumber:
CB0486794
Summenformel:
C10H10O
Molgewicht:
146.19
MOL-Datei:
530-93-8.mol

1,2,3,4-Tetrahydronaphthalin-2-on Eigenschaften

Schmelzpunkt:
18 °C(lit.)
Siedepunkt:
131 °C11 mm Hg(lit.)
Dichte
1.106 g/mL at 25 °C(lit.)
Brechungsindex
n20/D 1.560(lit.)
Flammpunkt:
>230 °F
storage temp. 
2-8°C
Aggregatzustand
Liquid or Low Melting Solid
Farbe
Clear pale yellow
Wasserlöslichkeit
insoluble
Sensitive 
Air Sensitive
BRN 
509386
InChIKey
KCKZIWSINLBROE-UHFFFAOYSA-N
CAS Datenbank
530-93-8(CAS DataBase Reference)
NIST chemische Informationen
2(1H)-Naphthalenone, 3,4-dihydro-(530-93-8)
EPA chemische Informationen
2-Tetralone (530-93-8)

Sicherheit

Kennzeichnung gefährlicher Xi,Xn
R-Sätze: 36/37/38-20/21/22
S-Sätze: 26-36
WGK Germany  3
10
TSCA  Yes
HS Code  29143900

1,2,3,4-Tetrahydronaphthalin-2-on Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

Liquid colorless to yellow

Verwenden

β-Tetralone is the 2-keto derivative of Tetralin. β-Tetralone was initially reported to be a metabolite of Tetralin but was later found to be just an artifact in the metabolism process. β-Tetralone is known to be biological marker in fossil fuels.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 4232, 1961 DOI: 10.1021/jo01069a014

läuterung methode

If reasonably pure, then fractionate it through an efficient column. Otherwise purify it via the bisulfite adduct. To a solution of NaHSO3 (32.5g, 0.31mol) in H2O (57mL) is added 95% EtOH (18mL) and set aside overnight. Any bisulfite-sulfate that separated is removed by filtration, and the filtrate is added to the tetralone (14.6g, 0.1mol) and shaken vigorously. The adduct separates in a few minutes as a white precipitate and is kept on ice for ~3.5hours with occasional shaking. The precipitate is collected, washed with 95% EtOH (13mL), then with Et2O (4 x 15mL, by stirring the suspension in the solvent, filtering and repeating the process). The colourless product is dried in air and stored in air tight containers in which it is stable for extended periods (yield is ~17g). This bisulfite (5g) is suspended in H2O (25mL), and Na2CO3.H2O (7.5g) is added (pH of solution is ~10). The mixture is then extracted with Et2O (5 x 10mL, i.e. until the aqueous phase does not test for tetralone — see below). Wash the combined extracts with 10% aqueous HCl (10mL), H2O (10mL, i.e. until the washings are neutral), dry (MgSO4), filter, evaporate and distil the residual oil using a Claisen flask under reduced pressure and in a N2 atmosphere. The pure tetralone is a colourless liquid b 70-71o/0.25mm (see also above). The yield is ~2g. Tetralone test: Dissolve a few drops of the tetralone solution (ethereal or aqueous) in 95% EtOH in a test tube and add 10 drops of 25% NaOH down the side of the tube. A deep blue colour develops at the interface with air. [Soffer et al. Org Synth Coll Vol IV 903 1963, Cornforth et al. J Chem Soc 689 1942, UV: Soffer et al. J Am Chem Soc 1556 1952.] The phenylhydrazone has m 108o [Crawley & Robinson J Chem Soc 2001 1938]. [Beilstein 7 H 370, 7 II 295, 7 III 1422, 7 IV 1018.]

1,2,3,4-Tetrahydronaphthalin-2-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,2,3,4-Tetrahydronaphthalin-2-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 193)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Springchem New Material Technology Co.,Limited
+8613917661608 +86-021-62885108
info@spring-chem.com China 2064 57
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20012 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15421 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 997 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
HaBo Hong Kong Co., Limited.
+86-25-18512596065
info@habotech.com CHINA 933 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4000 58
Changzhou Ditong Chemical Co.,Ltd
0519-88299272
info@edengenechem.com CHINA 2124 58

530-93-8(1,2,3,4-Tetrahydronaphthalin-2-on)Verwandte Suche:


  • JRH-04101, 3,4-Dihydronaphthalen-2(1H)-one, 97%
  • 1,2,3,4-Tetrahydro-2-oxonaphthalene
  • 2-Oxotetralin
  • NSC 87083
  • Tetralin-2-one
  • beta-Tetralone,95%
  • beta-Tetralone,99%
  • β-Tetralone,3,4-Dihydro-2(1H)-naphthalenone, 3,4-Dihydro-2-naphthol
  • 2(1H)-Naphthalenone
  • beta-Tetralone, 95% 5GR
  • Betafour hydrogen naphthaleneketone
  • beta-Tetralone 98%
  • n-ethylethanaminium acetate
  • 3,4-Dihydro-2-naphthol 3,4-Dihydro-2(1H)-naphthalenone
  • 1,2,3,4-Tetrahydro-2-naphthalenone for synthesis
  • 1,2,3,4-TETRAHYDRO-2-NAPHTHALENONE
  • 3,4-Dihydro-2,(1H)-naphtalenone
  • 3,4-DIHYDRO-2(1H)-NAPHTHALENONE
  • 3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE
  • 3,4-DIHYDRO-2-NAPHTHOL
  • 3,4-dihydro-2(1h)-naphthalenon
  • TETRALONE AN INTERMEDIATE OF SERTRALINE
  • 1,2,3,4-tetrahydronaphthalen-2-one
  • 2(1H)-Naphthalenone, 3,4-dihydro-
  • TETRALONE-2
  • 2-TETRALONE 97%
  • 3,4-DIHYDRO-2-OXONAPHTHALENE
  • 3,4-Dihydro-2(1H)-naphthalenone, 3,4-Dihydro-2-naphthol
  • 1,2,3,4-Tetrahydronaphthalene-2-one
  • 2-Oxotetrahydronaphthalene
  • 3,4-DIHYDRONAPHTHALEN-2(1H)-ONE
  • 2-TETRALONE
  • BETA-TETRALONE
  • B-TETRALONE
  • β-4-tetralone
  • BETA-TETRALONE,98%
  • Tetralon
  • 2-Tetralone,99%
  • 2-tetrahydronaphthone
  • β-TetraL
  • β-Tetralone
  • 530-93-8
  • C10
  • Carbonyl Compounds
  • Building Blocks
  • Ketones
  • Organic Building Blocks
  • Bioactive Small Molecules
  • Building Blocks
  • C10
  • Carbonyl Compounds
  • Cell Biology
  • Chemical Synthesis
  • Ketones
  • Organic Building Blocks
  • T
  • Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Copyright 2019 © ChemicalBook. All rights reserved