2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E

141286-78-4

CAS-Nr.: 141286-78-4

Englisch Name:: 2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E

Synonyma:: PEPA,inhibit,Inhibitor,iGluR,Ionotropic glutamate receptors;2-[2,6-Difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]acetamide;Acetamide, 2-[2,6-difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]-;2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide (PEPA)

CBNumber:: CB0972925

Summenformel:: C16H16F2N2O4S2

Molgewicht:: 402.44

MOL-Datei:: 141286-78-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 51

2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Eigenschaften

Siedepunkt:: 617.6±65.0 °C(Predicted)

Dichte: 1.47±0.1 g/cm3(Predicted)

storage temp.: protect from light

Löslichkeit: DMSO: >20mg/mL

Aggregatzustand: solid

pka: 10.44±0.40(Predicted)

Farbe: white

InChIKey: GTACSIONMHMRPD-UHFFFAOYSA-N

Sicherheit

WGK Germany	3

2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PEPA is an allosteric potentiator of AMPA desensitization.

Biologische Aktivität

Novel allosteric potentiator of AMPA receptor desensitization. Slows the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by glutamate with subunit (GluR3/4 > GluR1) and splice variant (flop > flip) selectivity. Ameliorates post-ischemic memory impairment in rats following i.v. administration.

Biochem/physiol Actions

2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.

2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 51)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	gao490372054@gamil.com	China	1250	58
Henan Allgreen Chemical Co.,LTD	+86-37155567971 +86-13633837469	info@allgreenchem.com	China	5986	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

141286-78-4()Verwandte Suche:

Dimethylsulfoxid 3-Pyridylamin

2-[2,6-Difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]acetamide
2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide (PEPA)
PEPA,inhibit,Inhibitor,iGluR,Ionotropic glutamate receptors
Acetamide, 2-[2,6-difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]-
141286-78-4
C16H16N2O4S2F2